Evidence map›Paper›PMID 35940832›Full record

Observational studyBMJ open2022

Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study.

Angelina Müller, Olga Anastasia Amberger, Anastasiya Glushan, Renate Klaaßen-Mielke, Claudia Witte, Marjan van den Akker, Robin Brünn, Ferdinand M Gerlach, Martin Beyer, Kateryna Karimova

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Angelina MüllerInstitute of General Practice, Goethe University, Frankfurt am Main, Germany a.mueller@allgemeinmedizin.uni-frankfurt.de.ORCID 0000-0003-0162-7000
Olga Anastasia AmbergerInstitute of General Practice, Goethe University, Frankfurt am Main, Germany.ORCID 0000-0002-2207-6036
Anastasiya GlushanInstitute of General Practice, Goethe University, Frankfurt am Main, Germany.
Renate Klaaßen-MielkeDepartment of Medical Informatics, Biometry and Epidemiology, Ruhr-Universitat Bochum, Bochum, Germany.
Claudia WitteInstitute for Applied Quality Improvement and Research in Health Care, AQUA, Gottingen, Germany.
Marjan van den AkkerInstitute of General Practice, Goethe University, Frankfurt am Main, Germany.ORCID 0000-0002-1022-8637
Robin BrünnInstitute of General Practice, Goethe University, Frankfurt am Main, Germany.
Ferdinand M GerlachInstitute of General Practice, Goethe University, Frankfurt am Main, Germany.
Martin BeyerInstitute of General Practice, Goethe University, Frankfurt am Main, Germany.
Kateryna KarimovaInstitute of General Practice, Goethe University, Frankfurt am Main, Germany.
Goethe University Frankfurt · DERuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare opioid prescription rates between patients enrolled in coordinated ambulatory care and patients receiving usual care.

designIn this retrospective cohort study, we analysed claims data for insured patients with non-specific/specific back pain or osteoarthritis of hip or knee from 2014 to 2017.

settingThe study was based on administrative data provided by the statutory health insurance fund 'Allgemeine Ortskrankenkasse', in the state of Baden-Wurttemberg, Germany.

participantsThe intervention group consisted of patients enrolled in a coordinated ambulatory healthcare model; the control group included patients receiving usual care. Outcomes were overall strong and weak opioid prescriptions. Generalised linear regression models were used to analyse the effect of the intervention.

resultsOverall, 46 001 (non-specific 18 787/specific 27 214) patients with back pain and 19 366 patients with osteoarthritis belonged to the intervention group, and 7038 (2803/4235) and 963 patients to the control group, respectively. No significant difference in opioid prescriptions existed between the groups. However, the chance of being prescribed strong opioids was significantly lower in the intervention group (non-specific back pain: Odds Ratio (OR) 0.735, 95% Confidential Interval (CI) 0.563 to 0.960; specific back pain: OR 0.702, 95% CI 0.577 to 0.852; osteoarthritis: OR 0.644, 95% CI 0.464 to 0.892). The chance of being prescribed weak opioids was significantly higher in patients with specific back pain (OR 1.243, 95% CI 1.032 to 1.497) and osteoarthritis (OR 1.493, 95% CI 1.037 to 2.149) in the intervention group.

conclusionCoordinated ambulatory healthcare appears to be associated with a lower prescription rate for strong opioids in patients with chronic musculoskeletal disorders. TRIAL REGISTRATION NUMBER: German Clinical Trials Register (DRKS00017548).

Indexed as

Analgesics, OpioidOsteoarthritisBack PainDelivery of Health CareHumansPrescriptionsRetrospective StudiesAnalgesics, OpioidBack painGENERAL MEDICINE (see Internal Medicine)Health & safety

Identifiers

PMID35940832
PMCPMC9364404
OpenAlexW4290673806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.