Evidence map›Paper›PMID 35940730›Full record

ReviewClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2022

Specific Challenges in Geriatric Cirrhosis and Hepatic Encephalopathy.

Jasmohan S Bajaj, Angela Gentili, James B Wade, Michael Godschalk

Open access · greenAbstract readReview
In one paragraph

Review in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jasmohan S BajajDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia. Electronic address: jasmohan.bajaj@vcuhealth.org.
Angela GentiliDivision of Geriatrics, Department of Medicine, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia.
James B WadeDivision of Neuropsychology, Department of Psychiatry, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia.
Michael GodschalkDivision of Geriatrics, Department of Medicine, Virginia Commonwealth University and Richmond VA Medical Center, Richmond, Virginia.
Hunter Holmes McGuire VA Medical Center · USVirginia Commonwealth University · US

Funding

Liver Cirrhosis Network: Clinical Research CentersU01DK130134 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI Jasmohan S Bajaj, ARUN J SANYAL · 2021 to 2026
$2.0M
Gut Microbiota in the Modulation of Outcomes after Liver TransplantR21TR003095 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI BAJAJ, JASMOHAN S, VERNA, ELIZABETH CLARICE · 2020 to 2021
$448k
Use of Patient Buddy Application to Disseminate Knowledge & Prevent ReadmissionR21HS024004 · AHRQ · VIRGINIA COMMONWEALTH UNIVERSITY · PI BAJAJ, JASMOHAN S · 2015 to 2016
$299k
Fecal Microbiota Transplant in Veterans with CirrhosisI01CX001076 · VA · VA VETERANS ADMINISTRATION HOSPITAL · PI BAJAJ, JASMOHAN S · 2015 to 2024
–
AHRQ HHS R21 HS024004CSRD VA I01 CX001076NCATS NIH HHS R21 TR003095NIDDK NIH HHS U01 DK130134
6 · The paper itself

Abstract

As the world's population ages, diseases predominantly found in the elderly now overlap with diseases that were thought to be the purview of younger patients. This includes chronic liver disease, which affects more than 2 billion people worldwide. Owing to the obesity epidemic (and associated metabolic diseases), nonalcoholic fatty liver disease has become the most common cause of chronic liver disease and cirrhosis. A major complication of cirrhosis is hepatic encephalopathy (HE), which becomes challenging to diagnose in elderly patients. HE is usually included in the differential diagnosis of acute delirium but not of reversible dementias. To illustrate this point, we present 2 cases of older patients that were misdiagnosed as having dementia and Parkinson's disease or a parkinsonian syndrome but had contributions from cirrhosis. Both cognitive impairment and tremor resolved with treatment of HE.

Indexed as

Hepatic EncephalopathyParkinson DiseaseAgedDiagnosis, DifferentialHumansLiver CirrhosisAlcoholDementiaEncephalAppLewy Body DementiaParkinson’s diseaseProgressive Supranuclear PalsyWernicke’s Encephalopathy

Identifiers

PMID35940730
PMCPMC9373233
OpenAlexW4289914632

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.