Evidence map›Paper›PMID 35940591›Full record

ArticleCancer science2022

Nonhematogenic circulating aneuploid cells confer inferior prognosis and therapeutic resistance in gliomas.

Mingxiao Li, Faliang Gao, Xiaohui Ren, Gehong Dong, Hongyan Chen, Alexander Y Lin, Daisy Dandan Wang, Mingyang Liu, Peter Ping Lin, Shaoping Shen and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Mingxiao LiDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Faliang GaoDepartment of Neurosurgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China.
Xiaohui RenDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Gehong DongDepartment of Pathology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Hongyan ChenDepartment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Alexander Y LinCytelligen, San Diego, California, USA.
Daisy Dandan WangCytelligen, San Diego, California, USA.
Mingyang LiuDepartment of Medicine, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, USA.
Peter Ping LinCytelligen, San Diego, California, USA.
Shaoping ShenDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Haihui JiangDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Chuanwei YangDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Xiaokang ZhangDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Xuzhe ZhaoDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Qinghui ZhuDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Ming LiDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Yong CuiDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.
Song LinDepartment of Neuro-Surgical Oncology, National Clinical Research Center for Neurological Diseases, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0001-5721-274X
Capital Medical University · CNCytel (United States) · USUniversity of Oklahoma Health Sciences Center · USZhejiang Provincial People's Hospital · CN

Funding

Capitals Funds for Health Improvement and Research 2020-2-1075National Natural Science Foundation of China 81771309
6 · The paper itself

Abstract

Aneuploidy is the hallmark of malignancy. Our previous study successfully detected nonhematogenic circulating aneuploidy cells (CACs) in types of gliomas. The current prospective clinical study aims to further precisely subcategorize aneuploid CACs, including CD31

Indexed as

GliomaNeoplastic Cells, CirculatingAneuploidyBiomarkers, TumorDrug Resistance, NeoplasmEndothelial CellsErbB ReceptorsGlial Fibrillary Acidic ProteinHumansIn Situ Hybridization, FluorescencePrognosisBiomarkers, TumorErbB ReceptorsGlial Fibrillary Acidic Proteinblood-brain-barrier, CD31-CTCCD31 + CTECgliomaprognosistherapy resistance

Identifiers

PMID35940591
PMCPMC9530864
OpenAlexW4288684602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.