Evidence map›Paper›PMID 35940566›Full record

ArticleClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2022

Perpetual observational studies: new strategies to support efficient implementation of observational studies and randomized trials in infectious diseases.

Nasreen Hassoun-Kheir, C Henri van Werkhoven, Jake Dunning, Thomas Jaenisch, Janko van Beek, Julia Bielicki, Christopher C Butler, Bruno Francois, Stephan Harbarth, Ana C Hernandez Padilla and 11 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05719259 (POS-VAP), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05719259 unknown statusnot on this map

POS-VAP: Perpetual Observational Study - Ventilator Associated Pneumonia

Typeobservational_patient_registrySponsorEuropean Clinical Research Alliance for Infectious Diseases (ECRAID)Ran2022 to 2026Enrolled20,000ConditionsVentilator Associated Pneumonia
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Article
  3. ERJ open research · 2025
    Article
  4. Review
  5. Observational
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Nasreen Hassoun-KheirInfection Control Program, Geneva University Hospitals and Faculty of Medicine, Geneva Switzerland.
C Henri van WerkhovenJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, the Netherlands.
Jake DunningPandemic Sciences Institute, University of Oxford, Oxford, UK.
Thomas JaenischHeidelberg Institute of Global Health (HIGH), Heidelberg University Hospital, Heidelberg, Germany.
Janko van BeekDepartment of Viroscience, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Julia BielickiInstitute for Infection and Immunity, St George's, University of London, London, UK; Infection Prevention and Control, Universitäts-Kinderspital Beider Basel, Basel, Switzerland.
Christopher C ButlerNuffield Department of Primary Care Health Sciences, Oxford University.
Bruno FrancoisMedical-Surgical Intensive Care Unit and Inserm CIC 1435 & UMR 1092, CHU Limoges, Limoges, France.
Stephan HarbarthInfection Control Program, Geneva University Hospitals and Faculty of Medicine, Geneva Switzerland.
Ana C Hernandez PadillaMedical-Surgical Intensive Care Unit and Inserm CIC 1435 & UMR 1092, CHU Limoges, Limoges, France.
Peter HorbyPandemic Sciences Institute, University of Oxford, Oxford, UK.
Marion KoopmansDepartment of Viroscience, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Pandemic and Disaster Preparedness Research Centre, Rotterdam, the Netherlands.
James LeePandemic Sciences Institute, University of Oxford, Oxford, UK.
Jesús Rodriguez-BañoInfectious Diseases and Microbiology, Hospital Universitario Virgen Macarena, Department of Medicine, University of Sevilla, Biomedicine Institute of Sevilla (IBiS), CSIC, Sevilla, Spain; Centro de Investigación Biomédica en Red en Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.
Evelina TacconelliDepartment of Infectious Diseases, University of Verona, Verona, Italy.
Yrene ThemistocleousPandemic Sciences Institute, University of Oxford, Oxford, UK.
Alike W van der VeldenJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, the Netherlands.
Marc BontenJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, the Netherlands.
Herman GoossensLaboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, University of Antwerp, Antwerp, Belgium.
Marlieke E A de KrakerInfection Control Program, Geneva University Hospitals and Faculty of Medicine, Geneva Switzerland. Electronic address: marlieke.dekraker@hcuge.ch.
ECRAID-Base consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Communicable DiseasesHumansRandomized Controlled Trials as TopicAntimicrobial resistanceEmerging infectious diseasesPerpetual observational studiesResearch networkStudy methodology

Identifiers

PMID35940566
PMCPMC9354481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.