Evidence map›Paper›PMID 35939914›Full record

ArticleJournal of substance abuse treatment2022

Use of long-acting injectable buprenorphine in the correctional setting.

Rosemarie A Martin, Justin Berk, Josiah D Rich, Augustine Kang, John Fritsche, Jennifer G Clarke

Open access · bronzeAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rosemarie A MartinCenter for Alcohol and Addiction Studies, Brown University School of Public Health, 121 S Main St, Providence, RI 02903, USA. Electronic address: Rosemarie_Martin@brown.edu.
Justin BerkWarren Alpert Medical School of Brown University, 222 Richmond St, Providence, RI 02903, USA; Rhode Island Department of Corrections, 40 Howard Avenue, Cranston, RI 02920, USA.
Josiah D RichWarren Alpert Medical School of Brown University, 222 Richmond St, Providence, RI 02903, USA; Department of Epidemiology, Brown University School of Public Health, 121 South Main Street, Providence, RI 02903, USA; The Center for Health and Justice Transformation, The Miriam Hospital, 1125 N. Main Street Providence, RI 02904, USA; Center of Biomedical Research Excellence on Opioids and Overdose, The Rhode Island Hospital, Providence, RI, USA.
Augustine KangCenter for Alcohol and Addiction Studies, Brown University School of Public Health, 121 S Main St, Providence, RI 02903, USA; Stanford University School of Medicine, 291 Campus Drive, Stanford, CA 94305, USA.
John FritscheCenter for Alcohol and Addiction Studies, Brown University School of Public Health, 121 S Main St, Providence, RI 02903, USA.
Jennifer G ClarkeWarren Alpert Medical School of Brown University, 222 Richmond St, Providence, RI 02903, USA.
Brown University · USRhode Island Hospital · US

Funding

Project 4: Neonatal Abstinence Syndrome (NAS): Fetus to First YearsP20GM125507 · NIGMS · RHODE ISLAND HOSPITAL · PI CURT G BECKWITH · 2018 to 2026
$23.4M
Using Implementation Interventions and Peer Recovery Support to Improve Opioid Treatment Outcomes in Community SupervisionU01DA050442 · NIDA · BROWN UNIVERSITY · PI BRINKLEY-RUBINSTEIN, LAUREN, MARTIN, ROSEMARIE A · 2019 to 2024
$12.6M
Substance Abuse Intervention/Outcome Research TrainingT32DA016184 · NIDA · BROWN UNIVERSITY · PI Damaris J. Rohsenow, JENNIFER W. TIDEY · 2003 to 2026
$6.1M
The Lifespan/Brown Criminal Justice Research Program on Substance Use and HIVR25DA037190 · NIDA · MIRIAM HOSPITAL · PI CURT G BECKWITH · 2014 to 2026
$3.5M
Injectable Extended-Release Buprenorphine (XR-B) in a Correctional Setting: A Pilot Randomized Controlled TrialK23DA055695 · NIDA · RHODE ISLAND HOSPITAL · PI Justin Berk · 2022 to 2026
$1.0M
Integrating Long-Acting Injectable Treatment to Improve Medication Adherence among Persons Living with HIV and Opioid Use DisorderR34DA055498 · NIDA · RHODE ISLAND HOSPITAL · PI LANGDON, KIRSTEN JOHNSON, RICH, JOSIAH D · 2022 to 2024
$692k
NIDA NIH HHS K23 DA055695NIDA NIH HHS R25 DA037190NIDA NIH HHS R34 DA055498NIDA NIH HHS T32 DA016184NIDA NIH HHS U01 DA050442NIGMS NIH HHS P20 GM125507
6 · The paper itself

Abstract

backgroundAs overdoses due to opioids rise, medications for opioid use disorder (MOUD) continue to be underemployed, resulting in limited access to potentially life-saving treatment. Substance use disorders are prevalent in individuals who are incarcerated, and these individuals are at increased risk for death postrelease due to overdose. Few jails and prisons offer MOUD and most limit access. Extended-release buprenorphine (XR-BUP), a novel monthly injectable MOUD formulation, could be uniquely poised to address treatment access in correctional settings.

methodsThis study linked a retrospective cohort design of statewide datasets to evaluate the real-world use of XR-BUP. The study included individuals (N = 54) who received XR-BUP while incarcerated from January 2019 through February 2022. The study was conducted at the Rhode Island Department of Corrections, with the nation's first comprehensive statewide correctional MOUD program.

resultsFifty-four individuals received a combined total of 162 injections during the study period. The study found no evidence of tampering with the injection site, indicating no attempts by participants to remove, hoard, or divert the medication. Sixty-one percent reported at least one adverse effect after injections were received, with an average of 2.8 side effects. Sixty-one percent of those released on XR-BUP engaged in MOUD after release, 30 % continued with XR-BUP.

conclusionsXR-BUP is feasible and acceptable in correctional settings. XR-BUP addresses administrative concerns of diversion that obstruct lifesaving MOUD and offers another safe and effective treatment option. Further studies and trials should continue to assess this novel medication's ability to treat opioid addiction in the correctional setting and upon release to the community.

Indexed as

BuprenorphineOpioid-Related DisordersDelayed-Action PreparationsHumansNaltrexoneNarcotic AntagonistsPrisonsRetrospective StudiesBuprenorphineDelayed-Action PreparationsNaltrexoneNarcotic AntagonistsAccess to careCorrectional facilitiesMedications for opioid use disorderXR-buprenorphine

Identifiers

PMID35939914
PMCPMC9743485
OpenAlexW4288734555

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.