Evidence map›Paper›PMID 35939764›Full record

ArticleBioconjugate chemistry2022

Organometallic

Hayden R Montgomery, Marco S Messina, Evan A Doud, Alexander M Spokoyny, Heather D Maynard

Open access · greenAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ultrafast Au(III)-Mediated Arylation of Cysteine.Journal of the American Chemical Society · 2024
    Article
  10. Efficient end-group functionalization and diblock copolymer synthesisChemical communications (Cambridge, England) · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hayden R MontgomeryDepartment of Chemistry and Biochemistry, University of California, 607 Charles E. Young Drive East, Los Angeles, California 90095-1569, United States.ORCID 0000-0002-6750-0830
Marco S MessinaDepartment of Chemistry and Biochemistry, University of California, 607 Charles E. Young Drive East, Los Angeles, California 90095-1569, United States.
Evan A DoudDepartment of Chemistry and Biochemistry, University of California, 607 Charles E. Young Drive East, Los Angeles, California 90095-1569, United States.ORCID 0000-0003-4561-4105
Alexander M SpokoynyDepartment of Chemistry and Biochemistry, University of California, 607 Charles E. Young Drive East, Los Angeles, California 90095-1569, United States.ORCID 0000-0002-5683-6240
Heather D MaynardDepartment of Chemistry and Biochemistry, University of California, 607 Charles E. Young Drive East, Los Angeles, California 90095-1569, United States.ORCID 0000-0003-3692-6289
California NanoSystems Institute · US

Funding

Inorganic Chemistry Tools for Bioconjugation, Recognition and ImagingR35GM124746 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Alexander Michael Spokoyny · 2017 to 2026
$4.0M
Circular Dichroism SpectrometerS10OD028491 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOO, JOSEPH A · 2020 to 2020
$100k
NIGMS NIH HHS R35 GM124746NIH HHS S10 OD028491
6 · The paper itself

Abstract

Bioconjugation techniques for biomolecule-polymer conjugation are numerous; however, slow kinetics and steric challenges generally necessitate excess reagents or long reaction times. Organometallic transformations are known to circumvent these issues; yet, harsh reaction conditions, incompatibility in aqueous media, and substrate promiscuity often limit their use in a biological context. The work reported herein demonstrates a facile and benign organometallic Au(III)

Indexed as

CysteinePolyethylene GlycolsIndicators and ReagentsOxidation-ReductionProteinsCysteineIndicators and ReagentsPolyethylene GlycolsProteins

Identifiers

PMID35939764
PMCPMC9573799
OpenAlexW4290725608

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.