ArticleProceedings of the National Academy of Sciences of the United States of America2022
Sex differences in the functional topography of association networks in youth.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Distinct neurobiological alterations during hedonic experience of rewards in attention deficit hyperactivity disorder and autism spectrum disorder: Multimodal evidence from neuroimaging meta-analyses.Molecular psychiatry · 2026Pooled it
- Neuroanatomy reflects individual variability in impulsivity in youth.Molecular psychiatry · 2026Article
- Regional sex differences in human cortical anatomy vary in their morphometric bases and overlap with sex chromosomal and gonadal influences.Nature communications · 2026Article
- Convergent and divergent brain-cognition development in early adolescence.Nature communications · 2026Article
- From Developmental Timing to Clinical Visibility: An Integrative Narrative Review of Sex-Related Neurocognitive Development.Children (Basel, Switzerland) · 2026Review
- The PMADS Project: A Longitudinal Multimodal Cohort Study to Understand Risk for Perinatal Mood and Anxiety Disorders.bioRxiv : the preprint server for biology · 2026Article
- Spatiotemporal dynamics of the human cortical functional hierarchy across the lifespan.Nature communications · 2026Article
- The effect of the "exposome" on developmental brain health and cognitive outcomes.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Lifestyle and Transcriptional Signatures Associated with Ethnicity/Race-Related Variations in the Functional Connectome.Research (Washington, D.C.) · 2026Article
- Neurodevelopmental considerations for transcranial magnetic stimulation trials in youth.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- An open, fully-processed data resource for studying mood and sleep variability in the developing brain.Aperture neuro · 2026Article
- Sex difference in the neural correlates of volitional eyes closing.Scientific reports · 2025Article
- Article
- Sex differences in response to violence: role of salience network expansion and connectivity on depression.Translational psychiatry · 2025Article
- Identification and External Validation of a Problem Cannabis Risk Network.Biological psychiatry · 2025Article
- Fractionation of sex differences in human cortical anatomy.bioRxiv : the preprint server for biology · 2025Article
- Neural Correlates of Burnout Syndrome Based on Electroencephalography (EEG)-A Mechanistic Review and Discussion of Burnout Syndrome Cognitive Bias Theory.Journal of clinical medicine · 2025Review
- Genetic risk predicts adolescent mood pathology via sexual differentiation of brain function and physiological aging.Nature communications · 2025Article
- Reproducible sex differences in personalised functional network topography in youth.The British journal of psychiatry : the journal of mental science · 2025Article
- Mapping individualized multi-scale hierarchical brain functional networks from fMRI by self-supervised deep learning.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
Abstract
Prior work has shown that there is substantial interindividual variation in the spatial distribution of functional networks across the cerebral cortex, or functional topography. However, it remains unknown whether there are sex differences in the topography of individualized networks in youth. Here, we leveraged an advanced machine learning method (sparsity-regularized non-negative matrix factorization) to define individualized functional networks in 693 youth (ages 8 to 23 y) who underwent functional MRI as part of the Philadelphia Neurodevelopmental Cohort. Multivariate pattern analysis using support vector machines classified participant sex based on functional topography with 82.9% accuracy (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.