ArticleProceedings of the National Academy of Sciences of the United States of America2022
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1.
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
What it found
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Who cites it
48 citing papers in PubMed, 56 citations in OpenAlex.
- Emerging threat of Oropouche virus: Clinical features, experimental models, and virulence.Virulence · 2026Review
- Rift Valley fever virus infects trophoblast cell lines in an LRP1-dependent manner.The Journal of general virology · 2026Article
- Review
- The Bunyamwera orthobunyavirus Gc glycoprotein head and stalk drives an infectious virion assembly pathway specific for the insect host.PLoS pathogens · 2026Article
- Nairobi sheep disease virus: an emerging threat with unresolved pathogenesis and zoonotic potential.Journal of virology · 2026Review
- Karimabad virus: A neglected sandfly-borne pathogen.Medicine · 2026Review
- Alveolar type 2 cell LRP1 is needed for surfactant phospholipid metabolism and pulmonary function in mice.Journal of lipid research · 2026Article
- Design of a neutralizing and protective pan-encephalitic alphavirus receptor decoy protein.Science translational medicine · 2026Article
- Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery.Cell reports. Medicine · 2026Article
- Type I interferon controls vertical transmission and fetoplacental infection of Oropouche virus.iScience · 2026Article
- A VLP-based mRNA vaccine elicits potent humoral and cellular immunity against Oropouche virus.mBio · 2026Article
- Article
- Replication competent La Crosse virus pseudotyped VSV vector system as vaccine and serological diagnostic reagent.Virus research · 2026Article
- LRP1 facilitates Jamestown Canyon virus infection of neurons.Journal of virology · 2025Article
- Oropouche virus: molecular virological characteristics and research progress of a neglected arbovirus.Virology journal · 2025Review
- Review
- A system to rapidly develop a bunyavirus pseudotyped virus neutralisation assay for pandemic preparedness.NPJ vaccines · 2025Article
- LRP8 is an entry receptor for tick-borne encephalitis viruses.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Charting the Proteins of Oropouche Virus.Viruses · 2025Review
- Review
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 1 country.
Madeline M SchwarzCenter for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213.ORCID 0000-0002-9038-4655
David A PriceDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110.
Safder S GanaieDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-9014-6577
Annie FengDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Nawneet MishraDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Ryan M HoehlDepartment of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213.
Farheen FatmaDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-6807-9670
Sarah H StubbsDepartment of Microbiology, Harvard Medical School, Boston, MA, 02115.ORCID 0000-0002-3261-191X
Sean P J WhelanDepartment of Molecular Microbiology, Washington University, St. Louis, MO, 63110.ORCID 0000-0003-1564-8590
Xiaoxia CuiGenome Engineering & Stem Cell Center (GESC@MGI), Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-3073-7332
Takeshi EgawaDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.ORCID 0000-0001-7489-1051
Daisy W LeungDepartment of Medicine, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-7189-9557
Gaya K AmarasingheDepartment of Pathology and Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Amy L HartmanCenter for Vaccine Research, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213.ORCID 0000-0002-0857-2973
Washington University in St. Louis · USUniversity of Pittsburgh · USHarvard University · US
Funding
Virology BSL4 CoreP01AI120943 · NIAID · WASHINGTON UNIVERSITY · PI Gaya K. Amarasinghe · 2016 to 2026
$30.2MThe transcription factor c-MYC in lymphocyte expansion and restriction of stemnessR01AI130152 · NIAID · WASHINGTON UNIVERSITY · PI Takeshi Egawa · 2017 to 2026
$4.6MIdentification and Characterization of Entry Factors Critical for Rift Valley Fever Virus Infection and PathogenesisR01AI161765 · NIAID · WASHINGTON UNIVERSITY · PI AMARASINGHE, GAYA K., HARTMAN, AMY L · 2021 to 2025
$3.7MLive-attenuated Rift Valley fever vaccines: comparative mechanisms of trans-placental transmission and vaccine efficacy for developing fetusesR01AI150792 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARTMAN, AMY L · 2020 to 2025
$3.7MMechanisms of actin cytoskeleton modulation by PneumovirusesR01AI140758 · NIAID · UNIVERSITY OF KENTUCKY · PI DUTCH, REBECCA E., LEUNG, DAISY W · 2018 to 2022
$3.3MNeuroprotective anti-inflammatory drugs as a novel combination therapy for neurological Rift Valley FeverR01NS101100 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARTMAN, AMY L · 2017 to 2021
$1.7MRole of the novel entry factor Lrp1 in in vivo tropism and pathogenesis of Rift Valley fever virusR21AI163603 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARTMAN, AMY L · 2021 to 2022
$442kNIAID NIH HHS P01 AI120943NIAID NIH HHS R01 AI130152NIAID NIH HHS R01 AI140758NIAID NIH HHS R01 AI150792NIAID NIH HHS R01 AI161765NIAID NIH HHS R21 AI163603NINDS NIH HHS R01 NS101100
Abstract
Oropouche orthobunyavirus (OROV;
Indexed as
Bunyaviridae InfectionsLow Density Lipoprotein Receptor-Related Protein-1OrthobunyavirusVirus InternalizationAnimalsGene Knockout TechniquesHumansMiceSouth AmericaLow Density Lipoprotein Receptor-Related Protein-1LRP1 protein, humanLrp1 protein, mousebunyavirusentry factorlipoproteinLrp1Oropouche virus
Identifiers
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.