Evidence map›Paper›PMID 35939687›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

RNA m

Chenbo Ding, Hao Xu, Zhibin Yu, Manolis Roulis, Rihao Qu, Jing Zhou, Joonseok Oh, Jason Crawford, Yimeng Gao, Ruaidhrí Jackson and 12 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Targeting intracellular mRNA mJournal of advanced research · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Epitranscriptomics Regulation of CD70, CD80, and TIGIT in Cancer Immunity.International journal of molecular sciences · 2025
    Article
  11. Article
  12. Thymic Bmi-1 hampers γδT17 generation and its derived RORγt-IL-17A signaling to delay cardiac aging.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Regulation and application of mScience China. Life sciences · 2025
    Review
  14. The Role of MClinical reviews in allergy & immunology · 2025
    Review
  15. Review
  16. Review
  17. Article
  18. ALKBH5 in development: decoding the multifaceted roles of mFrontiers in molecular biosciences · 2025
    Review
  19. Review
  20. Insights into the mCell & bioscience · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 4 institutions in 2 countries.

Chenbo DingDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.ORCID 0000-0002-3236-842X
Hao XuDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Zhibin YuDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Manolis RoulisDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Rihao QuDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Jing ZhouDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Joonseok OhDepartment of Chemistry, Yale University, New Haven, CT 06520.
Jason CrawfordDepartment of Chemistry, Yale University, New Haven, CT 06520.
Yimeng GaoSection of Hematology, Yale Cancer Center and Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520.
Ruaidhrí JacksonDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Esen SefikDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Simiao LiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Zheng WeiDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.ORCID 0000-0002-1859-0374
Mathias SkadowDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Zhinan YinZhuhai Precision Medical Center, Zhuhai People's Hospital, Jinan University, Zhuhai 519000, Guangdong, China.
Xinshou OuyangSection of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520.
Lei WangDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Qiang ZouDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Bing SuDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.ORCID 0000-0003-0871-7666
Weiguo HuDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Richard A FlavellDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT 06520.
Hua-Bing LiDepartment of Geriatrics, Center for Immune-Related Diseases, Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.ORCID 0000-0003-3573-6803
Yale University · USShanghai Jiao Tong University · CNJinan University · CNYale Cancer Center · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Howard Hughes Medical InstituteNCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

γδ T cells are an abundant T cell population at the mucosa and are important in providing immune surveillance as well as maintaining tissue homeostasis. However, despite γδ T cells' origin in the thymus, detailed mechanisms regulating γδ T cell development remain poorly understood.

Indexed as

AlkB Homolog 5, RNA DemethylaseIntraepithelial LymphocytesRNA, MessengerAnimalsJagged-1 ProteinMiceMice, KnockoutReceptor, Notch2Signal TransductionALKBH5 protein, mouseAlkB Homolog 5, RNA DemethylaseJag1 protein, mouseJagged-1 ProteinNotch2 protein, mouseReceptor, Notch2RNA, MessengerALKBH5developmental checkpointJagged1/Notch2 signalingRNA m6A modificationγδ T cell development

Identifiers

PMID35939687
PMCPMC9388086
OpenAlexW4290725161

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.