Evidence map›Paper›PMID 35939216›Full record

ArticleWiener medizinische Wochenschrift (1946)2023

Umbilical venous catheter- and peripherally inserted central catheter-associated complications in preterm infants with birth weight < 1250 g : Results from a survey in Austria and Germany.

Steffi Hess, Martin Poryo, Ralf Böttger, Axel Franz, Daniel Klotz, Knud Linnemann, Torsten Ott, Johannes Pöschl, Michael Schroth, Anja Stein and 12 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Wiener medizinische Wochenschrift (1946), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 2 countries.

Steffi HessDepartment of General Pediatrics and Neonatology, Saarland University Medical Center, Kirrberger Str., Building 9, 66421, Homburg, Germany.
Martin PoryoDepartment of Pediatric Cardiology, Saarland University Medical Center, Homburg, Germany.
Ralf BöttgerUniversity Children's Hospital, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Axel FranzUniversity Children's Hospital, Eberhard Karls University Tübingen, Tübingen, Germany.
Daniel KlotzDepartment of Neonatology, Center for Pediatrics, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Knud LinnemannUniversity Children's Hospital, Greifswald University Hospital, Greifswald, Germany.
Torsten OttUniversity Children's Hospital, University Hospital Muenster, Münster, Germany.
Johannes PöschlUniversity Children's Hospital, Heidelberg University Hospital, Heidelberg, Germany.
Michael SchrothChildren's Hospital Nürnberg, Nürnberg, Germany.
Anja SteinUniversity Children's Hospital, Essen University Hospital, Essen, Germany.
Elisabeth RalserUniversity Children's Hospital, Medical University of Innsbruck, Innsbruck, Austria.
Heiko ReutterDivision of Neonatology and Pediatric Intensive Care Medicine, Department of Pediatric and Adolescent Medicine, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
Ulrich H ThomeUniversity Children's Hospital, University of Leipzig Medical Center, Leipzig, Germany.
Christian WiegChildren's Hospital Aschaffenburg, Aschaffenburg, Germany.
Anne EhrlichInterdisziplinäres Zentrum für Klinische Studien (IZKS), Johannes Gutenberg-Universität, Mainz, Germany.
Christian RuckesInterdisziplinäres Zentrum für Klinische Studien (IZKS), Johannes Gutenberg-Universität, Mainz, Germany.
Stefan WagenpfeilInstitute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University Medical Center, Homburg/Saar, Germany.
Michael ZemlinDepartment of General Pediatrics and Neonatology, Saarland University Medical Center, Kirrberger Str., Building 9, 66421, Homburg, Germany.
Cihan PapanDepartment of Medical Microbiology and Hospital Hygiene, Saarland University Medical Center, Homburg, Germany.
Arne SimonDepartment of Pediatric Hematology and Oncology, Infectious Diseases, Saarland University Medical Center, Homburg, Germany.
Johannes BayDepartment of General Pediatrics and Neonatology, Saarland University Medical Center, Kirrberger Str., Building 9, 66421, Homburg, Germany.
Sascha MeyerDepartment of General Pediatrics and Neonatology, Saarland University Medical Center, Kirrberger Str., Building 9, 66421, Homburg, Germany. sascha.meyer@uks.eu.ORCID http://orcid.org/0000-0001-6016-4558
Saarland University · DEJohannes Gutenberg University Mainz · DEEssen University Hospital · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEHeidelberg University · DEKlinikum Aschaffenburg · DEOtto-von-Guericke-Universität Magdeburg · DEUniversität Innsbruck · ATUniversitätsmedizin Greifswald · DEUniversity Children's Hospital Tübingen · DEUniversity Hospital Leipzig · DEUniversity Hospital Münster · DEUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveUmbilical venous catheters (UVC) and peripherally inserted central catheters (PICC) are commonly used in preterm infants but have been associated with a number of serious complications. We performed a survey in Austria and Germany to assess the use of UVCs and PICCs in preterm infants with a birth weight < 1250 g and associated rates of catheter-related adverse events.

methodsElectronic survey of participating centers of the NeoVitaA trial. Main outcome parameter was the reported rates of UVC- and PICC-associated complications (infection, thrombosis, emboli, organ injury, arrhythmia, dislocation, miscellaneous).

resultsIn total, 20 neonatal intensive care units (NICU) providing maximal intensive care in Austria and Germany (level I) were contacted, with a senior neonatologist response rate of 12/20 (60%). The reported rates for UVC with a dwell time of 1-10 days were bacterial infection: 4.2 ± 3.4% (range 0-10%); thrombosis: 7.3 ± 7.1% (0-20%); emboli: 0.9 ± 2.0% (0-5%); organ injury: 1.1 ± 1.9% (0-5%); cardiac arrhythmia: 2.2 ± 2.5% (0-5%); and dislocation: 5.4 ± 8.7% (0-30%); and for PICCs with a dwell time of 1-14 days bacterial infection: 15.0 ± 3.4% (range 2.5-30%); thrombosis; 4.3 ± 3.5% (0-10%); emboli: 0.8 ± 1.6% (0-5%); organ injury: 1.5 ± 2.3% (0-5%); cardiac arrhythmia: 1.5 ± 2.3% (0-5%), and dislocation: 8.5 ± 4.6% (0-30%).

conclusionThe catheter-related complication rates reported in this survey differed between UVCs and PICCs and were higher than those reported in the literature. To generate more reliable data on this clinically important issue, we plan to perform a large prospective multicenter randomized controlled trial investigating the non-inferiority of a prolonged UVC dwell time (up to 10 days) against the early change (up to 5 days) to a PICC.

Indexed as

Bacterial InfectionsCatheterization, Central VenousThrombosisAustriaBirth WeightCathetersHumansInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightProspective StudiesRetrospective StudiesEmboliInfectionOrgan injuryPeripherally inserted central catheterSurveyThrombosisUmbilical venous catheterVery low birth weight infants

Identifiers

PMID35939216
PMCPMC10147741
OpenAlexW4290631487

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.