Evidence map›Paper›PMID 35938982›Full record

ReviewBrain and behavior2022

Cancer-related stroke: Exploring personalized therapy strategies.

Yu-Jie Chen, Rui-Guo Dong, Meng-Meng Zhang, Chao Sheng, Peng-Fei Guo, Jie Sun

Open access · goldAbstract readReview
In one paragraph

Review in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Mechanical thrombectomy for the treatment of large vessel occlusion due to cancer-related cerebral embolism: A systematic review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu-Jie ChenDepartment of Neurological Rehabilitation, Xuzhou Central Hospital, Xuzhou city, P.R. China.
Rui-Guo DongDepartment of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou city, P.R. China.
Meng-Meng ZhangDepartment of Neurological Rehabilitation, Xuzhou Central Hospital, Xuzhou city, P.R. China.
Chao ShengDepartment of Neurological Rehabilitation, Xuzhou Central Hospital, Xuzhou city, P.R. China.
Peng-Fei GuoDepartment of Neurological Rehabilitation, Xuzhou Central Hospital, Xuzhou city, P.R. China.
Jie SunDepartment of Neurological Rehabilitation, Xuzhou Central Hospital, Xuzhou city, P.R. China.
Xuzhou Central Hospital · CNXuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer and ischemic stroke are two common diseases that threaten human health and have become the main causes of death in the world. It is estimated that one-in-ten patients with ischemic stroke have concomitant cancer, and this incidence is expected to increase as improvements in medical technology extends the life expectancy of cancer patients. DISCUSSION: Cancer-related stroke (CRS) refers to unexplained ischemic stroke in patients with active cancer that cannot be explained by current stroke mechanisms. Available evidence suggests that CRS accounts for 5-10% of embolic stroke of undetermined source (ESUS). Although the incidence of CRS is gradually increasing, its underlying pathogenesis remains unclear. Also, there is no consensus on acute treatment and secondary prevention of stroke.

conclusionIn this review, we retrospectively analyzed the incidence, mechanisms of CRS, its potential as a new stroke subtype, options for acute treatment, secondary prevention strategies, and disease progression, with the aim of attempting to explore personalized therapy strategies.

Indexed as

Intracranial EmbolismIschemic StrokeNeoplasmsStrokeHumansRetrospective StudiesRisk FactorsSecondary Preventioncancer-related strokeembolic stroke of undetermined sourcehypercoagulabilityindividualized therapypathogenesisstroke subtype

Identifiers

PMID35938982
PMCPMC9480895
OpenAlexW4295540522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.