Evidence map›Paper›PMID 35938873›Full record

ArticleMicrobiology spectrum2022

Characterization of Streptococcus pneumoniae Macrolide Resistance and Its Mechanism in Northeast China over a 20-Year Period.

Xiuzhen Zhou, Jianhua Liu, Zhijie Zhang, Bing Cui, Yanling Wang, Yue Zhang, Hailin Xu, Guixue Cheng, Yong Liu, Xiaosong Qin

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Prevalence ofHuman vaccines & immunotherapeutics · 2024
    Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Epidemiology, changing resistance trends and serotypes ofFrontiers in cellular and infection microbiology · 2025
    Article
  9. Article
  10. Article
  11. Detection of Macrolide-ResistantThe Malaysian journal of medical sciences : MJMS · 2024
    Article
  12. Article
  13. Article
  14. Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiuzhen ZhouDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Jianhua LiuDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Zhijie ZhangDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Bing CuiDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Yanling WangDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Yue ZhangDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Hailin XuDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Guixue ChengDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Yong LiuDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.
Xiaosong QinDepartment of Laboratory Medicine, Shengjing Hospital of China Medical University, Liaoning Clinical Research Center for Laboratory Medicine, Shenyang, China.ORCID 0000-0002-7171-6298
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the resistance of Streptococcus pneumoniae to β-lactams, macrolides, and tetracyclines, treatment alternatives have become increasingly limited worldwide. We aim to describe the characterization of erythromycin-resistant S. pneumoniae (ERSP) strains in northeastern China over a period of 20 years. A total of 1,240 ERSP strains were collected and classified into five groups based on the ages of the patients. Etest strips and Kirby-Bauer disk diffusion were performed for drug susceptibility testing. The capsule swelling test was used for capsule typing. The phenotype of drug resistance was detected by the erythromycin and clindamycin double-disk method. The

Indexed as

Drug Resistance, Multiple, BacterialStreptococcus pneumoniaeAmoxicillinAnti-Bacterial AgentsCeftriaxoneChinaChloramphenicolClindamycinErythromycinMacrolidesMeropenemMicrobial Sensitivity TestsPenicillinsRetrospective StudiesStreptogramin BTetracyclineAmoxicillinAnti-Bacterial AgentsCeftriaxoneChloramphenicolClindamycinErythromycinMacrolidesMeropenemPenicillinsStreptogramin BTetracyclineTrimethoprim, Sulfamethoxazole Drug Combinationantibiotic resistanceermBmacrolidesMDRmultidrug resistanceStreptococcus pneumoniae

Identifiers

PMID35938873
PMCPMC9602527
OpenAlexW4290643763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.