Evidence map›Paper›PMID 35938851›Full record

ArticleJournal of bacteriology2022

A Defect in Lipoprotein Modification by Lgt Leads to Abnormal Morphology and Cell Death in Escherichia coli That Is Independent of Major Lipoprotein Lpp.

S Legood, D Seng, I G Boneca, N Buddelmeijer

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Identification and characterization of the lipoproteinProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Identification and Characterization of the LipoproteinbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

S LegoodInstitut Pasteurgrid.428999.7, Université de Paris, CNRS UMR6047, INSERM U1306, Unité de Biologie et Génétique de la paroi bactérienne, Paris, France.
D SengInstitut Pasteurgrid.428999.7, Université de Paris, CNRS UMR6047, INSERM U1306, Unité de Biologie et Génétique de la paroi bactérienne, Paris, France.
I G BonecaInstitut Pasteurgrid.428999.7, Université de Paris, CNRS UMR6047, INSERM U1306, Unité de Biologie et Génétique de la paroi bactérienne, Paris, France.
N BuddelmeijerInstitut Pasteurgrid.428999.7, Université de Paris, CNRS UMR6047, INSERM U1306, Unité de Biologie et Génétique de la paroi bactérienne, Paris, France.ORCID 0000-0003-1116-3625
Centre National de la Recherche Scientifique · FR

Funding

Institut Carnot Infectious Diseases Global Care 16 CARN 0023-01 project iLiNTInstitut PasteurInvestissement d'Avenir program - Laboratoire d'Excellence ANR-10-LABX-62-IBEIDPasteur Paris University (PPU) International PhD program
6 · The paper itself

Abstract

Lgt is an essential enzyme in proteobacteria and therefore a potential target for novel antibiotics. The effect of Lgt depletion on growth, morphology, and viability was studied in Escherichia coli to assess whether absence of Lgt leads to cell death. Two Lgt depletion strains were used in which

Indexed as

Escherichia coli InfectionsEscherichia coli ProteinsAnti-Bacterial AgentsArabinoseBacterial Outer Membrane ProteinsCell DeathEscherichia coliHumansLipoproteinsTransferasesAnti-Bacterial AgentsArabinoseBacterial Outer Membrane ProteinsEscherichia coli ProteinsLipoproteinsLpp protein, E coliphosphatidylglycerol glyceryl transferaseTransferasescell envelopecell viabilityEscherichia coliLgtLppviability

Identifiers

PMID35938851
PMCPMC9487459
OpenAlexW4290723763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.