Evidence map›Paper›PMID 35938149›Full record

ArticleIDCases2022

Encephalopathy induced by high levels of ceftriaxone in the blood and cerebrospinal fluid.

Takahiro Minamii, Hayato Shimizu, Kei Irie, Hiroaki Nishioka

Open access · goldAbstract readCase Reports
In one paragraph

Article in IDCases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Takahiro MinamiiDepartment of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo 650-0047, Japan.
Hayato ShimizuDepartment of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo 650-0047, Japan.
Kei IrieFaculty of Pharmaceutical Science, Kobe Gakuin University, Kobe, Hyogo 650-8586, Japan.
Hiroaki NishiokaDepartment of General Internal Medicine, Kobe City Medical Center General Hospital, Kobe, Hyogo 650-0047, Japan.
Kobe City Medical Center General Hospital · JPKobe Gakuin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftriaxone is commonly used to treat bacterial infections. Encephalopathy is a rare adverse effect of ceftriaxone therapy, and most cases have been diagnosed based on medical history. We report a case of a 73-year-old woman with ceftriaxone-associated encephalopathy, which was confirmed by measuring the ceftriaxone levels in the blood and cerebrospinal fluid. She regularly underwent hemodialysis. She received intravenous ceftriaxone at a dose of 1 g/day for 4 days for enteritis, and mental status began to be disturbed during the therapy. Six days after ceftriaxone discontinuation, her consciousness level rapidly improved. Thus, ceftriaxone-associated encephalopathy was suspected. High ceftriaxone levels in the blood and cerebrospinal fluid were observed while the patient had disturbed consciousness. This case indicated that high ceftriaxone levels in the blood and cerebrospinal fluid were related to development of encephalopathy. The estimation of ceftriaxone levels may be useful for an accurate diagnosis.

Indexed as

CeftriaxoneCerebrospinal fluidEncephalopathyEnd-stage renal disease

Identifiers

PMID35938149
PMCPMC9352448
OpenAlexW4288046382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.