Evidence map›Paper›PMID 35938135›Full record

ReviewFrontiers in nutrition2022

Wheat Biofortification: Utilizing Natural Genetic Diversity, Genome-Wide Association Mapping, Genomic Selection, and Genome Editing Technologies.

Om Prakash Gupta, Amit Kumar Singh, Archana Singh, Gyanendra Pratap Singh, Kailash C Bansal, Swapan K Datta

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Stable pleotropic loci controlling the accumulation of multiple nutritional elements in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Om Prakash GuptaICAR-Indian Institute of Wheat and Barley Research, Karnal, India.
Amit Kumar SinghICAR-National Bureau of Plant Genetic Resources, New Delhi, India.
Archana SinghDepartment of Botany, Hansraj College, University of Delhi, New Delhi, India.
Gyanendra Pratap SinghICAR-Indian Institute of Wheat and Barley Research, Karnal, India.
Kailash C BansalNational Academy of Agricultural Sciences, New Delhi, India.
Swapan K DattaDepartment of Botany, University of Calcutta, Kolkata, India.
Indian Institute of Wheat and Barley Research · INNational Bureau of Plant Genetic Resources · INNational Academy of Agricultural Sciences · INUniversity of Calcutta · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alleviating micronutrients associated problems in children below five years and women of childbearing age, remains a significant challenge, especially in resource-poor nations. One of the most important staple food crops, wheat attracts the highest global research priority for micronutrient (Fe, Zn, Se, and Ca) biofortification. Wild relatives and cultivated species of wheat possess significant natural genetic variability for these micronutrients, which has successfully been utilized for breeding micronutrient dense wheat varieties. This has enabled the release of 40 biofortified wheat cultivars for commercial cultivation in different countries, including India, Bangladesh, Pakistan, Bolivia, Mexico and Nepal. In this review, we have systematically analyzed the current understanding of availability and utilization of natural genetic variations for grain micronutrients among cultivated and wild relatives, QTLs/genes and different genomic regions regulating the accumulation of micronutrients, and the status of micronutrient biofortified wheat varieties released for commercial cultivation across the globe. In addition, we have also discussed the potential implications of emerging technologies such as genome editing to improve the micronutrient content and their bioavailability in wheat.

Indexed as

genome editinghidden hungermicronutrientsphytateQTLs

Identifiers

PMID35938135
PMCPMC9348810
OpenAlexW4285093144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.