Evidence map›Paper›PMID 35938014›Full record

ArticleFrontiers in genetics2022

Transcriptional progressive patterns from mild to severe renal ischemia/reperfusion-induced kidney injury in mice.

Dong Lai, Lei Wang, Jia-Rui Li, Chen Chen, Wen-Lei Zhao, Qing Yuan, Xin Ma, Xu Zhang

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dong LaiDepartment of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, China.
Lei WangDepartment of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, China.
Jia-Rui LiBiomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Chen ChenBiomedical Innovation Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Wen-Lei ZhaoDepartment of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, China.
Qing YuanDepartment of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, China.
Xin MaDepartment of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, China.
Xu ZhangDepartment of Urology, The Third Medical Center, Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNBeijing Shijitan Hospital · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The renal ischemia/reperfusion (I/R)-induced acute kidney injury incidence after nephron-sparing surgery for localized renal tumors is 20%, but the biological determinant process of postoperative acute kidney injury remains unclear. Using Gene Expression Omnibus database (GSE192883) and several bioinformatics analyses (discrete time points analysis, gene set enrichment analysis, dynamic network biomarker analysis, etc), combined with the establishment of the I/R model for verification, we identified three progressive patterns involving five core pathways confirmed using gene set enrichment analysis and six key genes (

Indexed as

dynamic network biomarker analysisgene set enrichment analysisprogressive patterns of I/R kidney injuryrenal ischemia/reperfusion injurytime series analysis

Identifiers

PMID35938014
PMCPMC9355309
OpenAlexW4286560587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.