Evidence map›Paper›PMID 35937762›Full record

ArticleAfrican journal of laboratory medicine2022

Formulation of phage cocktails and evaluation of their interaction with antibiotics in inhibiting carbapenemase-producing

Noutin F Michodigni, Atunga Nyachieo, Juliah K Akhwale, Gabriel Magoma, Abdoul-Salam Ouédraogo, Andrew N Kimang'a

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in African journal of laboratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Noutin F MichodigniDepartment of Molecular Biology and Biotechnology, Pan African University Institute for Basic Sciences Technology and Innovation (PAUSTI), Nairobi, Kenya.ORCID https://orcid.org/0000-0003-2304-2601
Atunga NyachieoDepartment of Reproductive Health and Biology, Institute of Primate Research (IPR), Nairobi, Kenya.ORCID https://orcid.org/0000-0002-7906-5311
Juliah K AkhwaleDepartment of Zoology, School of Biological Sciences, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Nairobi, Kenya.ORCID https://orcid.org/0000-0001-8878-6957
Gabriel MagomaDepartment of Molecular Biology and Biotechnology, Pan African University Institute for Basic Sciences Technology and Innovation (PAUSTI), Nairobi, Kenya.ORCID https://orcid.org/0000-0001-8517-3442
Abdoul-Salam OuédraogoDepartment of Medical Microbiology Laboratories, Souro-Sanou Teaching Hospital, Bobo-Dioulasso, Burkina Faso.ORCID https://orcid.org/0000-0002-8539-3768
Andrew N Kimang'aDepartment of Medical Microbiology, College of Health Sciences, Jomo Kenyatta University of Agriculture and Technology (JKUAT), Nairobi, Kenya.ORCID https://orcid.org/0000-0002-3423-4484
Jomo Kenyatta University of Agriculture and Technology · KEInstitute of Primate Research · KEWest African Health Organisation · BF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The development of alternative control measures, such as phage therapy or adjunctive therapy, is urgently needed to manage the dissemination of carbapenemase-producing Objective: This study aimed to evaluate the therapeutic potential of formulated phage cocktails and their interaction with select antibiotics in inhibiting the growth of carbapenemase-producing Methods: The study was conducted from February 2021 to October 2021 at the Institute of Primate Research, Nairobi, Kenya. Phage cocktails were formulated based on the morphology and biological properties of precipitated Results: The precipitated bacteriophages were members of Conclusion: This study demonstrated that the two-phage cocktail in combination with imipenem was able to synergistically delay the increase in carbapenemase-producing

Indexed as

absorbancesantibioticscarbapenemaseKlebsiella pneumoniaephage cocktail

Identifiers

PMID35937762
PMCPMC9350486
OpenAlexW4285385478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.