Evidence map›Paper›PMID 35937693›Full record

ArticleFrontiers in cellular and infection microbiology2022

Metagenomic profiling of ocular surface microbiome changes in

Yana Fu, Jie Wu, Dandan Wang, Tiankun Li, Xinwei Shi, Lu Li, Minying Zhu, Zuhui Zhang, Xinxin Yu, Qi Dai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Ocular Surface Microbiota Alterations Following FS-LASIK and Their Association With Postoperative Dry Eye.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
  5. Article
  6. Evaluation of ocular surface microbiota in children with blepharoconjunctivitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Exploring the Ocular Surface Microbiome and Tear Proteome in Glaucoma.International journal of molecular sciences · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Investigating the Ocular Surface Microbiome: What Can It Tell Us?Clinical ophthalmology (Auckland, N.Z.) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yana FuSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Jie WuSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Dandan WangSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Tiankun LiTianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Nankai University Affiliated Eye Hospital, Tianjin, China.
Xinwei ShiSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Lu LiSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Minying ZhuSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Zuhui ZhangSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Xinxin YuSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Qi DaiSchool of Optometry and Ophthalmology, the Eye Hospital of Wenzhou Medical University, Wenzhou, China.
Affiliated Eye Hospital of Wenzhou Medical College · CNWenzhou Medical University · CNFirst Affiliated Hospital of Soochow University · CNTianjin Medical University Eye Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To compare the ocular surface and meibum microbial communities of humans with Methods: Conjunctival sac and meibum samples from 25 DB patients and 11 healthy controls were analyzed using metagenomic next-generation sequencing (mNGS). Results: The alpha-diversity of the conjunctival sac microbiome of the Conclusions: Proteobacteria's increased prevalence may indicate ocular microbial community instability. The species

Indexed as

AcinetobacterBlepharitisMicrobiotaBacteriaHumansMeibomian GlandsProteobacteriaDemodex blepharitismeibummetagenomic next-generation sequencingmicrobial communitiesocular surface

Identifiers

PMID35937693
PMCPMC9354880
OpenAlexW4286562054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.