Evidence map›Paper›PMID 35937691›Full record

ArticleFrontiers in cellular and infection microbiology2022

Gut Microbiota Correlates With Clinical Responsiveness to Erythropoietin in Hemodialysis Patients With Anemia.

Yifan Zhu, Yuyan Tang, Haidong He, Ping Hu, Weiqian Sun, Meiping Jin, Lishun Wang, Xudong Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yifan ZhuDepartment of Nephrology, Minhang Hospital, Fudan University, Shanghai, China.
Yuyan TangDepartment of Nephrology, Minhang Hospital, Fudan University, Shanghai, China.
Haidong HeDepartment of Nephrology, Minhang Hospital, Fudan University, Shanghai, China.
Ping HuDepartment of Nephrology, Minhang Hospital, Fudan University, Shanghai, China.
Weiqian SunDepartment of Nephrology, Minhang Hospital, Fudan University, Shanghai, China.
Meiping JinDepartment of Nephrology, Minhang Hospital, Fudan University, Shanghai, China.
Lishun WangCenter for Traditional Chinese Medicine and Gut Microbiota, Institute of Fudan-Minhang Academic Health System, Minhang Hospital, Fudan University, Shanghai, China.
Xudong XuDepartment of Nephrology, Minhang Hospital, Fudan University, Shanghai, China.
Fudan University · CNMinhang District Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main treatment for renal anemia in end-stage renal disease (ESRD) patients on hemodialysis is erythropoiesis (EPO). EPO hyporesponsiveness (EH) in dialysis patients is a common clinical problem, which is poorly understood. Recent searches reported that gut microbiota was closely related to the occurrence and development of ESRD. This study aims to explore the changes in gut microbiota between ESRD patients with different responsiveness to EPO treatment. We compared the gut microbiota from 44 poor-response (PR) and 48 good-response (GR) hemodialysis patients treated with EPO using 16S rDNA sequencing analysis. The results showed that PR patients displayed a characteristic composition of the gut microbiome that clearly differed from that of GR patients. Nine genera (

Indexed as

AnemiaErythropoietinGastrointestinal MicrobiomeKidney Failure, ChronicHumansRenal DialysisErythropoietinAnemiaEPO hyporesponsivenessESRD (End Stage Renal Disease)gut microbiotahemodialysis

Identifiers

PMID35937691
PMCPMC9355670
OpenAlexW4286685611

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.