ArticleNefrologia : publicacion oficial de la Sociedad Espanola Nefrologia2022
[Treatment of patients with COVID-19 on Hemodialysis: Efficacy of Remdesivir].
Article in Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThere is no standard therapy for hemodialysis (HD) patients with COVID-19. Data on remdesivir in HD patients with COVID-19 are scarce.
methodsWe retrospectively analyzed 25 HD patients with COVID-19 treated with remdesivir.
resultsThe median age of the patients was 78 years (range, 45-92 years) and was predominantly male (84%). A total of 44% of the patients had mild disease, 36% had moderate-1, and 20% had moderate-2. The most common symptoms were fever (76%) and coughing (44%). The most common comorbidity was renal failure (100%), followed by hypertension (60%) and cardiac disease (44%). The most frequent biomarker was elevated creatinine (100%), followed by C-reactive protein (80%), lymphopenia (76%), and D-dimer (68%). C-reactive protein levels decreased significantly before and after remdesivir administration (p < 0.001). Two patients showed deterioration, but none died. All patients recovered from COVID-19 and no adverse effects of treatment with remdesivir were observed.
conclusionOur study suggests the safe use of remdesivir in HD patients with COVID-19.
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