Evidence map›Paper›PMID 35937580›Full record

ArticleReports (MDPI)2021

NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors.

Shivanand Pudakalakatti, Alessandra Audia, Anirudh Mukhopadhyay, José S Enriquez, Dontrey Bourgeois, Nabihah Tayob, Niki M Zacharias, Steven W Millward, Daniel Carson, Mary C Farach-Carson and 4 more

Open access · goldAbstract read
In one paragraph

Article in Reports (MDPI), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Identifying the Metabolic Signatures of PPARD-Overexpressing Gastric Tumors.International journal of molecular sciences · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Shivanand PudakalakattiDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Alessandra AudiaDepartment of Translational Molecular Pathology, The University of Texas MD Anderson Center Center, Houston, TX 77030, USA.
Anirudh MukhopadhyayDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.ORCID 0000-0001-5955-5674
José S EnriquezDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Dontrey BourgeoisDepartment of Statistics, Rice University, Houston, TX 77005, USA.
Nabihah TayobDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Niki M ZachariasMD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77054, USA.
Steven W MillwardDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.
Daniel CarsonDepartment of BioSciences, Rice University, Houston, TX 77005, USA.
Mary C Farach-CarsonMD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77054, USA.ORCID 0000-0002-4526-3088
Frederick F LangMD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77054, USA.
Amy B HeimbergerMD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77054, USA.
Krishna P BhatDepartment of Translational Molecular Pathology, The University of Texas MD Anderson Center Center, Houston, TX 77030, USA.
Pratip K BhattacharyaDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA.ORCID 0000-0002-0625-252X
The University of Texas MD Anderson Cancer Center · USRice University · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Tropism Enhanced Oncolytic Adenovirus for the Treatment of Brain TumorsP50CA127001 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Juan Fueyo · 2008 to 2026
$41.2M
UNIVERSITY OF TEXAS MD ANDERSON SPORE IN OVARIAN CANCERP50CA083639 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BAST, ROBERT C · 1999 to 2015
$33.0M
Texas Center for Cancer NanomedicineU54CA151668 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FERRARI, MAURO · 2010 to 2014
$12.4M
CANCER PREVENTION EDUCAT--STUDENT RESEARCH EXPERIENCESR25CA056452 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Shine Chang · 1992 to 2026
$6.9M
Training Program in Biostatistics for Cancer ResearchT32CA096520 · NCI · RICE UNIVERSITY · PI KIMMEL, MAREK, YUAN, YING · 2003 to 2023
$4.5M
Targeted Hyperpolarized Molecular Beacons for Colorectal Cancer DetectionR21EB031217 · NIBIB · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BHATTACHARYA, PRATIP K. · 2021 to 2023
$648k
(PQC5)Early Detection Pancreatic Cancer by Hyperpolarized Silicon NanoparticlesR21CA185536 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BHATTACHARYA, PRATIP K. · 2014 to 2015
$383k
NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA083639NCI NIH HHS P50 CA127001NCI NIH HHS R21 CA185536NCI NIH HHS R25 CA056452NCI NIH HHS T32 CA096520NCI NIH HHS U54 CA151668NIBIB NIH HHS R21 EB031217
6 · The paper itself

Abstract

"Tumor-educated platelets" have recently generated substantial interest for the diagnosis of cancer. We hypothesized that tumor educated platelets from patients with brain tumors will reflect altered metabolism compared to platelets from healthy volunteers. Here, in a pilot study, we have employed nuclear magnetic resonance (NMR) spectroscopy in platelets from brain tumor patients to demonstrate altered metabolism compared to the platelets obtained from healthy volunteers.

Indexed as

biomarkersbrain tumormetabolomicsNMR spectroscopyplatelets

Identifiers

PMID35937580
PMCPMC9352435
OpenAlexW3204671758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.