Evidence map›Paper›PMID 35937504›Full record

ArticlePersonalized medicine in psychiatry

The United States index of socioeconomic deprivation for individuals (USiDep).

Boadie W Dunlop, Jeffrey J Rakofsky, David Mischoulon, Helen S Mayberg, Becky Kinkead, Andrew A Nierenberg, Thomas R Ziegler, Maurizio Fava, Mark H Rapaport

Abstract read
In one paragraph

Article in Personalized medicine in psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Association of Air Pollution and Socioeconomic Deprivation with Depression and Pain.International journal of environmental research and public health · 2026
    Article
  2. Article
  3. Impact of Social Determinants of Health on Cardiovascular Disease.Journal of the American Heart Association · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Racial/ethnic disparities in chronic wounds: Perspectives on linking upstream factors to health outcomes.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Boadie W DunlopDepartment of Psychiatry and Behavioral Sciences, Emory University, 12 Executive Park Drive NE, 3rd Floor Atlanta, GA 30329, USA.
Jeffrey J RakofskyDepartment of Psychiatry and Behavioral Sciences, Emory University, 12 Executive Park Drive NE, 3rd Floor Atlanta, GA 30329, USA.
David MischoulonDepartment of Psychiatry, Massachusetts General Hospital, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA.
Helen S MaybergDepartment of Psychiatry and Neurology, Mount Sinai School of Medicine, Mount Sinai West Floor 10 Room 10G-47, 1000 10th Ave, New York, NY 10019, USA.
Becky KinkeadDepartment of Psychiatry and Behavioral Sciences, Emory University, 12 Executive Park Drive NE, 3rd Floor Atlanta, GA 30329, USA.
Andrew A NierenbergDepartment of Psychiatry, Massachusetts General Hospital, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA.
Thomas R ZieglerDepartment of Medicine, Emory University Atlanta, 100 Woodruff Circle, Atlanta BA 30322, USA.
Maurizio FavaDepartment of Psychiatry, Massachusetts General Hospital, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA.
Mark H RapaportDepartment of Psychiatry and Behavioral Sciences, Emory University, 12 Executive Park Drive NE, 3rd Floor Atlanta, GA 30329, USA.

Funding

Testing an Imaging Biomarker for Treatment Stratification in Major DepressionR01MH073719 · NIMH · EMORY UNIVERSITY · PI DUNLOP, BOADIE W · 2006 to 2018
$5.8M
Omega-3 Fatty Acids for MDD with High Inflammation: A Personalized ApproachUG3AT008857 · NCCIH · EMORY UNIVERSITY · PI RAPAPORT, MARK HYMAN · 2015 to 2016
$2.4M
NCCIH NIH HHS UG3 AT008857NIMH NIH HHS R01 MH073719
6 · The paper itself

Abstract

Background: Individuals experiencing socioeconomic deprivation consistently demonstrate poorer physical and mental health. Income alone is inadequate as a measure of socioeconomic status (SES); a better measure for assessing the deprivation status of individuals is needed. Methods: The New Zealand Index of Socioeconomic Deprivation for Individuals, a validated, eight-item measure of deprivation, was modified to create the United States Index of Socioeconomic Deprivation for Individuals (USiDep). The questionnaire was administered to patients with major depressive disorder participating in two clinical trials. Spearman's correlation coefficients evaluated associations between USiDep scores with income and other measures associated with deprivation. Results: The USiDep was completed by 118 participants, demonstrating adequate internal consistency (Crohnbach's alpha = 0.766) and strong item-total correlations. USiDep scores were moderately correlated with past-year personal income (Spearman's rho = -0.362, p < .001) and several other measures related to deprivation, including body mass index, level of education, quality of life, severity of childhood traumatic events, self-reported physical health, and negative life events. Patients scoring 5 on the USiDep (the highest possible score, indicating greater deprivation) had significantly lower rates of remission after 12 weeks of treatment than those scoring ≤ 4 (1/12, 8.3% vs 40/98, 40.8%, respectively, p = .03), whereas the lowest income group showed no significant associations with outcomes. Conclusion: The USiDep is a valid, brief questionnaire for assessing SES that has utility for clinical research and may serve as a predictor of treatment outcomes in clinical trials. Validation of the USiDep in healthy controls and other medically and psychiatrically ill populations is warranted.

Indexed as

Clinical TrialDepressionMental healthNutritionPovertySocioeconomic factors

Identifiers

PMID35937504
PMCPMC9355266

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.