Evidence map›Paper›PMID 35937091›Full record

ArticleNature photonics2022

Metasurface-based bijective illumination collection imaging provides high-resolution tomography in three dimensions.

Masoud Pahlevaninezhad, Yao-Wei Huang, Majid Pahlevani, Brett Bouma, Melissa J Suter, Federico Capasso, Hamid Pahlevaninezhad

Open access · greenAbstract read
In one paragraph

Article in Nature photonics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 64 citations in OpenAlex.

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  11. In Vivo Intelligent Fluorescence Endo-Microscopy by Varifocal Meta-Device and Deep Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Masoud PahlevaninezhadHarvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Yao-Wei HuangHarvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Majid PahlevaniDepartment of Electrical and Computer Engineering, Queen's University, Kingston, Ontario, Canada.
Brett BoumaHarvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Melissa J SuterHarvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Federico CapassoHarvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.
Hamid PahlevaninezhadHarvard Medical School and Massachusetts General Hospital, Boston, MA, USA.
Harvard University · USQueen's University · CA

Funding

TRD3: Percutaneous and Interstitial ImagingP41EB015903 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Brett E Bouma · 2012 to 2026
$22.4M
Phenotyping Asthma for Bronchial Thermoplasty: Airway Smooth Muscle Structure and FunctionR01HL133664 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SUTER, MELISSA J · 2017 to 2021
$3.7M
Early Detection and Diagnosis of Lung Cancer with EndomicroscopyR01CA255326 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Brett E Bouma, Melissa J Suter · 2021 to 2026
$3.2M
NCI NIH HHS R01 CA255326NHLBI NIH HHS R01 HL133664NIBIB NIH HHS P41 EB015903
6 · The paper itself

Abstract

Microscopic imaging in three dimensions enables numerous biological and clinical applications. However, high-resolution optical imaging preserved in a relatively large depth range is hampered by the rapid spread of tightly confined light due to diffraction. Here, we show that a particular disposition of light illumination and collection paths liberates optical imaging from the restrictions imposed by diffraction. This arrangement, realized by metasurfaces, decouples lateral resolution from depth-of-focus by establishing a one-to-one correspondence (bijection) along a focal line between the incident and collected light. Implementing this approach in optical coherence tomography, we demonstrate tissue imaging at 1.3 μm wavelength with ~ 3.2 μm lateral resolution, maintained nearly intact over 1.25 mm depth-of-focus, with no additional acquisition or computation burden. This method, termed bijective illumination collection imaging, is general and might be adapted across various existing imaging modalities.

Identifiers

PMID35937091
PMCPMC9355264
OpenAlexW4212991166

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.