Evidence map›Paper›PMID 35937087›Full record

ArticleiScience2022

Increased induction of

Juan Irure-Ventura, Lara Belmar-Vega, Gema Fernández-Fresnedo, Elena González-López, Carolina Castro-Hernández, Emilio Rodrigo-Calabia, Milagros Heras-Vicario, Juan Carlos Ruiz San Millán, Marcos López-Hoyos

Abstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Juan Irure-VenturaImmunology Service, University Hospital Marqués de Valdecilla, 39008 Santander, Spain.
Lara Belmar-VegaTransplantation and Autoimmunity Laboratory, Research Institute "Marqués de Valdecilla" (IDIVAL), 39011 Santander, Spain.
Gema Fernández-FresnedoTransplantation and Autoimmunity Laboratory, Research Institute "Marqués de Valdecilla" (IDIVAL), 39011 Santander, Spain.
Elena González-LópezImmunology Service, University Hospital Marqués de Valdecilla, 39008 Santander, Spain.
Carolina Castro-HernándezImmunology Service, University Hospital Marqués de Valdecilla, 39008 Santander, Spain.
Emilio Rodrigo-CalabiaTransplantation and Autoimmunity Laboratory, Research Institute "Marqués de Valdecilla" (IDIVAL), 39011 Santander, Spain.
Milagros Heras-VicarioTransplantation and Autoimmunity Laboratory, Research Institute "Marqués de Valdecilla" (IDIVAL), 39011 Santander, Spain.
Juan Carlos Ruiz San MillánTransplantation and Autoimmunity Laboratory, Research Institute "Marqués de Valdecilla" (IDIVAL), 39011 Santander, Spain.
Marcos López-HoyosImmunology Service, University Hospital Marqués de Valdecilla, 39008 Santander, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different immune-mediated diseases have been described after SARS-CoV-2 vaccination, with antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) being one of the possible side effects. In this study, a total of 35 patients presented ANCA for the first time during 2021, with the number during 2019 being 15. Twenty-seven out of thirty-five patients developed ANCA after vaccination. Two of them developed these antibodies after receiving the first dose (7.4%), and 25 patients developed ANCA after the second dose of the vaccine (92.6%), with BNT162b2 being the main vaccine received by these patients. In 97.1% of the patients who developed ANCA during 2021, the positivity of ANCA was accompanied by systemic involvement, with renal and respiratory tracts being the main organs affected. Therefore, an increase in the development of AAV has been observed during 2021 in comparison with 2019, which could be due to the administration of SARS-CoV-2 vaccine.

Indexed as

Clinical findingDiseaseHealth sciences

Identifiers

PMID35937087
PMCPMC9344695

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.