Evidence map›Paper›PMID 35936784›Full record

ReviewFrontiers in molecular biosciences2022

Redesigning Enzymes for Biocatalysis: Exploiting Structural Understanding for Improved Selectivity.

Yaoyu Ding, Gustavo Perez-Ortiz, Jessica Peate, Sarah M Barry

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  8. Review
  9. Advanced Electroanalysis for Electrosynthesis.ACS organic & inorganic Au · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yaoyu DingDepartment of Chemistry, Faculty of Natural, Mathematical and Engineering Sciences, King's College London, London, United Kingdom.
Gustavo Perez-OrtizDepartment of Chemistry, Faculty of Natural, Mathematical and Engineering Sciences, King's College London, London, United Kingdom.
Jessica PeateDepartment of Chemistry, Faculty of Natural, Mathematical and Engineering Sciences, King's College London, London, United Kingdom.
Sarah M BarryDepartment of Chemistry, Faculty of Natural, Mathematical and Engineering Sciences, King's College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery of new enzymes, alongside the push to make chemical processes more sustainable, has resulted in increased industrial interest in the use of biocatalytic processes to produce high-value and chiral precursor chemicals. Huge strides in protein engineering methodology and

Indexed as

biocatalysisenzymesprotein engineeringrational designregioselectivitystereoselectivitystructural biology

Identifiers

PMID35936784
PMCPMC9355150

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.