Evidence map›Paper›PMID 35936520›Full record

ArticleIranian journal of public health2022

A Retrospective Study of Serum Calcium Status in Tehran, Iran (105,128 Samples, from 2009-2018).

Dariush D Farhud, Marjan Zarif-Yeganeh, Atefeh Mehrabi, Ali-Reza Afshari, Mohammad Bagher Rokni, Keyvan Majidi, Maryam Jalali, Ali Akbar Amir Zargar, Abdolfattah Sarafnejad, Hamid Reza Sadeghipour and 4 more

Open access · goldAbstract read
In one paragraph

Article in Iranian journal of public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Dariush D FarhudSchool of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Marjan Zarif-YeganehFarhud Genetic Clinic, Tehran, Iran.
Atefeh MehrabiFarhud Genetic Clinic, Tehran, Iran.
Ali-Reza AfshariPediatric Gastroenterology and Hepatology Research Center, Zabol University of Medical Sciences, Zabol, Iran.
Mohammad Bagher RokniSchool of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Keyvan MajidiNoor Pathobiology Laboratory, Tehran, Iran.
Maryam JalaliNoor Pathobiology Laboratory, Tehran, Iran.
Ali Akbar Amir ZargarNoor Pathobiology Laboratory, Tehran, Iran.
Abdolfattah SarafnejadNoor Pathobiology Laboratory, Tehran, Iran.
Hamid Reza SadeghipourNoor Pathobiology Laboratory, Tehran, Iran.
Shaghayegh ZokaeiFarhud Genetic Clinic, Tehran, Iran.
Farideh KhosraviNoor Pathobiology Laboratory, Tehran, Iran.
Mahmoud JalaliNoor Pathobiology Laboratory, Tehran, Iran.
Mohammad KhazeniDepartment of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Noor Eye Hospital · IRTehran University of Medical Sciences · IROmid Fertility Clinic · IRIranian Academy of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRZabol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Calcium is a necessary mineral for life to keep the body and bones healthy. Various factors including hormones, diet, age, and gender affect serum calcium status. The aim of this sturdy was to assess the serum calcium level (SCL) of Tehran population, which has about 10 million multi-Ethnic populations and represents from the whole country. Methods: In this retrospective study, the measured SCL of 105,128 individuals referred to different laboratories of Tehran, Iran were evaluated and its relationship with the age, gender, seasons, and different years during 2009-2018, were analyzed. Results: After excluding outliers, 91,257samples remained, which 61162 (58.64%) and 30,095 (41.36%) were female and male, respectively. The mean SCL was 9.36 (9.35, 9.37) mg/dl (95%CI). The highest and lowest SCLs were 3.1 and 18.2mg/dl, respectively. From the total study population, 74127 (81.23%) had normal SCLs, 14110 (15.46%) had hypocalcemia, and 3020 (3.31%) had hypercalcemia. SCLs were normal in 83.6% of men and 79.66% of women. Women had a significantly higher frequency of hypocalcemia compared to men (17.2% vs. 12.83%, p<0.0001). Conclusion: Normal and abnormal SCLs were significantly different in age groups and in both genders. It means that gender and age affect SCLs. Every year of increasing age, reduces the chance of hypercalcemia by 40%, significantly. Age seems to affect hypercalcemia more than hypocalcemia. Age in men increases the risk of hypocalcemia, and reduces the risk of hypocalcemia in women. Therefore, it is recommended to encourage dietary calcium intake among premenopausal women and older men.

Indexed as

CalciumHypercalcemiaHypocalcemiaIran

Identifiers

PMID35936520
PMCPMC9288392
OpenAlexW4224286630

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.