ArticleACS omega2022
Development of a Nonenzymatic Colorimetric Sensor for the Detection of Uric Acid Based on Ionic Liquid-Mediated Nickel Nanostructures.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 30 citations in OpenAlex.
- Green-synthesized iron-zinc oxide nanomaterials immobilized onRSC advances · 2026Article
- Uricase-free and cost-effective colorimetric assay for uric acid based on CoBTC metal-organic frameworks.Scientific reports · 2025Article
- Glancing Angle Deposition in Gas Sensing: Bridging Morphological Innovations and Sensor Performances.Nanomaterials (Basel, Switzerland) · 2025Review
- Optical detection of uric acid based on a citric acid functionalized copper-doped biochar nanozyme.RSC advances · 2024Article
- From waste to wealth: iron oxide doped hydroxyapatite-based biosensor for the colorimetric detection of ascorbic acid.RSC advances · 2024Article
- Uric acid quantificationRSC advances · 2024Article
- Article
- Bioconjugation of nanozyme and natural enzyme to enable a one-step cascade reaction for the detection of metabolites.Analytical and bioanalytical chemistry · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uric acid (UA) is a metabolic byproduct of purine nucleotides and is excreted as a urine component. Abnormalities in UA metabolism cause localized inflammation due to crystal deposition and can lead to various diseases. In the current study, we successfully fabricated a biosensor based on 1-H-3-methylimidazolium acetate (ionic liquid, IL)-capped nickel nanoparticles (NiNPs) for the detection of uric acid in test samples. The structures of IL-capped NiNPs and their precursors were characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, and X-ray diffraction. The IL-capped NiNPs possessed intrinsic peroxidase-like properties and displayed selective UA quenching after interacting with 3,3',5,5'-tetramethylbenzidine (TMB) solution. Different parameters such as pH, time, IL, TMB, and UA concentration were optimized to obtain the best results for the proposed sensor. The UA biosensor shows good responses in the linear range from 1 × 10
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Registered trials
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