Evidence map›Paper›PMID 35936378›Full record

ArticleComputational and mathematical methods in medicine2022

Peritumor Edema Serves as an Independent Predictive Factor of Recurrence Patterns and Recurrence-Free Survival for High-Grade Glioma.

Jie Chen, Hui Qiu, Rui Chen, Jiani Huang, Liang Chen, Juncheng Wan, Qi Chen, Longzhen Zhang

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jie ChenSchool of Medical Imaging, Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0001-6803-2066
Hui QiuDepartment of Radiation Oncology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0002-5819-0965
Rui ChenSchool of Medical Imaging, Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0001-8847-5294
Jiani HuangSchool of Medical Imaging, Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0001-8796-3325
Liang ChenSchool of Medical Imaging, Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0002-3021-8997
Juncheng WanSchool of Medical Imaging, Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0002-0825-4000
Qi ChenSchool of Medical Imaging, Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0001-9119-2463
Longzhen ZhangSchool of Medical Imaging, Xuzhou Medical University, Xuzhou 221000, China.ORCID https://orcid.org/0000-0002-5786-1560
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study is aimed at analyzing the factors affecting the recurrence patterns and recurrence-free survival (RFS) of high-grade gliomas (HGG). Methods: Eligible patients admitted to the Affiliated Hospital of Xuzhou Medical University were selected. Subsequently, the effects of some clinical data including age, gender, WHO pathological grades, tumor site, tumor size, clinical treatments, and peritumoral edema (PTE) area and molecular markers (Ki-67, MGMT, IDH-1, and p53) on HGG patients' recurrence patterns and RFS were analyzed. Results: A total number of 77 patients were enrolled into this study. After analyzing all the cases, it was determined that tumor size and tumor site had a significant influence on the recurrent patterns of HGG, and PTE was an independent predict factor of recurrence patterns. Specifically, when the PTE was mild (<1 cm), the recurrence pattern tended to be local; in contrast, HGG was more likely to progress to marginal recurrence and distant recurrence. Furthermore, age and PTE were significantly associated with RFS; the median RFS of the population with PTE < 1 cm (23.60 months) was obviously longer than the population with PTE ≥ 1 cm (5.00 months). Conclusions: PTE is an independent predictor of recurrence patterns and RFS for HGG. Therefore, preoperative identification of PTE in HGG patients is crucially important, which is helpful to accurately estimate the recurrence pattern and RFS.

Indexed as

Brain NeoplasmsGliomaEdemaHumans

Identifiers

PMID35936378
PMCPMC9348930
OpenAlexW4288058242

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.