Evidence map›Paper›PMID 35936358›Full record

ArticleComputational and mathematical methods in medicine2022

Expression of POT1-AS1 in GC Tissue, Its Effect on Biological Behavior of Gastric Cancer, and Its Significance on Prognosis of Gastric Cancer.

Li Jiang, Lie Yang, Yun Dai, Guangming Yang, Shuyin Pan

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Li JiangDepartment of Pathology, Liyang People's Hospital, 213300, China.
Lie YangDepartment of Pathology, Liyang People's Hospital, 213300, China.ORCID https://orcid.org/0000-0002-9481-7120
Yun DaiDepartment of Pathology, Liyang People's Hospital, 213300, China.
Guangming YangDepartment of Pathology, Liyang People's Hospital, 213300, China.
Shuyin PanDepartment of Pathology, Liyang People's Hospital, 213300, China.
Lishui City People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To study the correlation between gold in GC and biological indicators of gastric cancer (GC) and its effect on prognosis and correlation of POT1-AS1 with GC cellular growth, and to explore its impact in the processes of GC, to supply histological basis for medical treatment of GC. Methods: From September 2019 to December 2021, 80 pairs of GAC specimens and healthy para-carcinoma tissue were immediately stored in paraformaldehyde solution. POT1-AS1 levels in 77 postoperative patients with GC were detected by immunohistochemical method. The correlation of the above indexes and the relationship between the above indexes and the biological behavior and prognosis of GC were analyzed. Results: POT1-AS1 was strongly displayed in GAC specimens, and the difference between groups was statistically significant ( Conclusion: The correlation between TIMP-1 of GASTRIC cancer mesenchymal cells of POT1-AS1 and VEGF and Ki-67-Li suggests that TIMP-1 produced by mesenchymal cells can facilitate tumor progression and lead to poor prognosis by promoting tumor cell proliferation. VEGF can strengthen tumor angiogenesis and then promote tumor cell proliferation, which has an adverse effect on the prognosis. Ki-67-LI is correlated to the medical biological behavior and prognosis of the tumor, reflecting the malignant process of the tumor.

Indexed as

RNA, Long NoncodingStomach NeoplasmsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansKi-67 AntigenLymphatic MetastasisPrognosisShelterin ComplexTelomere-Binding ProteinsTissue Inhibitor of Metalloproteinase-1Vascular Endothelial Growth Factor AKi-67 AntigenPOT1 protein, humanRNA, Long NoncodingShelterin ComplexTelomere-Binding ProteinsTissue Inhibitor of Metalloproteinase-1Vascular Endothelial Growth Factor A

Identifiers

PMID35936358
PMCPMC9355756
OpenAlexW4288701310

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.