Evidence map›Paper›PMID 35936086›Full record

ArticleFrontiers in chemistry2022

Apigenin-Mn(II) loaded hyaluronic acid nanoparticles for ulcerative colitis therapy in mice.

Feng Lv, Yuchen Zhang, Qiao Peng, Xinxin Zhao, Datao Hu, Jinpeng Wen, Kailai Liu, Ruilin Li, Ke Wang, Jinyao Sun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Review
  3. Study on the effect of modified diosmetin for ulcerative colitis.Journal of materials science. Materials in medicine · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Drug design, development and therapy · 2024
    Review
  11. Article
  12. Flavonoids inInternational journal of molecular sciences · 2023
    Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Feng LvSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Yuchen ZhangSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Qiao PengHealth Science Center, Xi'an Jiaotong University, Xi'an, China.
Xinxin ZhaoSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Datao HuSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Jinpeng WenSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Kailai LiuSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Ruilin LiInternal Medicine, Xi'an Jiaotong University Hospital, Xi'an, China.
Ke WangSchool of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Jinyao SunDepartment of Pharmacy, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xi'an Jiaotong University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic idiopathic inflammatory bowel disease characterized by rapid progression and frequent comorbidities that make its treatment challenging. Nanomaterial-based strategies have been extensively studied to target the GI mucosal immune system in recent years. Herein, we propose a novel apigenin-Mn(II) loaded sodium hyaluronate nanoparticles where apigenin (API) was incorporated in the Mn

Indexed as

API-Mn(II) complexDSSmanganese ionregulatory effectulcerative colitis

Identifiers

PMID35936086
PMCPMC9354835
OpenAlexW4286698513

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.