Evidence map›Paper›PMID 35936045›Full record

ArticleJournal of arrhythmia2022

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases.

Arthur A M Wilde, Christopher Semsarian, Manlio F Márquez, Alireza Sepehri Shamloo, Michael J Ackerman, Euan A Ashley, Back Sternick Eduardo, Héctor Barajas-Martinez, Elijah R Behr, Connie R Bezzina and 38 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Geographical and Ethnic Heterogeneity in Genetic Dilated Cardiomyopathies.International journal of molecular sciences · 2026
    Pooled it
  2. Incidence and predictors of major arrhythmic events after myocarditis: a systematic review and meta-analysis.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Hypokalaemia and bradycardia unmask the loss-of-function phenotype of a Brugada Syndrome SCN5A mutation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  9. Article
  10. De Novo ACTN2 Variant in a Chinese Neonate With Left Ventricular Non-Compaction and Metabolic Disturbances: A Rare Case Report.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Article
  11. Mapping the Functional Landscape ofmedRxiv : the preprint server for health sciences · 2025
    Article
  12. Brazilian Atrial Fibrillation Guidelines - 2025.Arquivos brasileiros de cardiologia · 2025
    Article
  13. Article
  14. Article
  15. SCN5A variant type-dependent risk prediction in Brugada syndrome.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Novel causativeFrontiers in genetics · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Arthur A M WildeHeart Centre, Department of Cardiology, Amsterdam Universitair Medische Centra Amsterdam The Netherlands.
Christopher SemsarianAgnes Ginges Centre for Molecular Cardiology at Centenary Institute University of Sydney Sydney Australia.
Manlio F MárquezInstituto Nacional de Cardiología Ignacio Chávez Ciudad de México Mexico.
Alireza Sepehri ShamlooDepartment of Electrophysiology Heart Center at University of Leipzig Leipzig Germany.
Michael J AckermanDepartments of Cardiovascular Medicine, Pediatric and Adolescent Medicine, and Molecular Pharmacology & Experimental Therapeutics; Divisions of Heart Rhythm Services and Pediatric Cardiology; Windland Smith Rice Genetic Heart Rhythm Clinic and Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic Rochester MN USA.
Euan A AshleyDepartment of Cardiovascular Medicine Stanford University Stanford CA USA.
Back Sternick EduardoArrhythmia and Electrophysiology Unit Biocor Institute Minas Gerais Brazil.
Héctor Barajas-MartinezCardiovascular Research Lankenau Institute of Medical Research Wynnewood PA USA.
Elijah R BehrCardiovascular Clinical Academic Group, Institute of Molecular and Clinical Sciences, St. George's University of London; St. George's University Hospitals NHS Foundation Trust London UKMayo Clinic HealthcareLondon.
Connie R BezzinaAmsterdam UMC Heart Center, Department of Experimental Cardiology Amsterdam The Netherlands.
Jeroen BreckpotCenter for Human Genetics University Hospitals Leuven Leuven Belgium.
Philippe CharronSorbonne Université Centre Paris France.
Priya ChockalingamCardiac Wellness Institute Chennai India.
Lia CrottiCenter for Cardiac Arrhythmias of Genetic Origin, Istituto Auxologico Italiano, IRCCS Milan Italy.
Michael H GollobInherited Arrhythmia and Cardiomyopathy Program, Division of Cardiology University of Toronto Toronto ON Canada.
Steven LubitzCardiac Arrhythmia Service Massachusetts General Hospital and Harvard Medical School Boston MA USA.
Naomasa MakitaNational Cerebral and Cardiovascular Center Research Institute Suita Japan.
Seiko OhnoDepartment of Bioscience and Genetics, National Cerebral and Cardiovascular Center Suita Japan.
Martín Ortiz-GengaClinical Department, Health in Code A Coruña Spain.
Luciana SacilottoArrhythmia Unit, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo Brazil.
Eric Schulze-BahrInstitute for Genetics of Heart Diseases University Hospital Münster Münster Germany.
Wataru ShimizuDepartment of Cardiovascular Medicine Graduate School of Medicine Tokyo Japan.
Nona SotoodehniaCardiovascular Health Research Unit, Division of Cardiology, Department of Medicine University of Washington Seattle WA USA.
Rafik TadrosCardiovascular Genetics Center, Department of Medicine, Montreal Heart Institute Université de Montréal Montreal Canada.
James S WareNational Heart and Lung Institute and MRC London Institute of Medical Sciences Imperial College London London UK.
David S WinlawCincinnati Children's Hospital Medical Centre University of Cincinnati Cincinnati OH USA.
Elizabeth S KaufmanMetrohealth Medical Center Case Western Reserve University Cleveland OH USA.
Takeshi AibaDepartment of Clinical Laboratory Medicine and Genetics, National Cerebral and Cardiovascular Center, Suita Osaka Japan.
Andreas BollmannDepartment of Electrophysiology Heart Center Leipzig at University of Leipzig Leipzig Germany.
Jong-Il ChoiDivision of Cardiology, Department of Internal Medicine, Korea University Anam Hospital Korea University College of Medicine Seoul Republic of Korea.
Aarti DalalDepartment of Pediatrics, Division of Cardiology Vanderbilt University School of Medicine Nashville TN USA.
Francisco DarrieuxArrhythmia Unit, Instituto do Coração, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo São Paulo Brazil.
John GiudicessiDepartment of Cardiovascular Medicine (Divisions of Heart Rhythm Services and Circulatory Failure and the Windland Smith Rice Genetic Heart Rhythm Clinic), Mayo Clinic Rochester MN USA.
Mariana GuerchicoffDivision of Pediatric Arrhythmia and Electrophysiology, Italian Hospital of Buenos Aires Buenos Aires Argentina.
Kui HongDepartment of Cardiovascular Medicine The Second Affiliated Hospital of Nanchang University Nanchang China.
Andrew D KrahnDivision of Cardiology University of British Columbia Vancouver Canada.
Ciorsti Mac IntyreDepartment of Cardiovascular Medicine, Division of Heart Rhythm Services, Windland Smith Rice Genetic Heart Rhythm Clinic, Mayo Clinic Rochester MN USA.
Judith A MackallCenter for Cardiac Electrophysiology and Pacing, University Hospitals Cleveland Medical Center Case Western Reserve University School of Medicine Cleveland OH USA.
Lluís MontInstitut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS). Barcelona, Spain; Centro de Investigacion Biomedica en Red en Enfermedades Cardiovasculares (CIBERCV), Madrid Spain.
Carlo NapolitanoMolecular Cardiology, Istituti Clinici Scientifici Maugeri, IRCCS Pavia Italy.
Pablo Ochoa JuanCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid Spain.
Petr PeichlDepartment of Cardiology Institute for Clinical and Experimental Medicine Prague Czech Republic.
Alexandre C PereiraLaboratory of Genetics and Molecular Cardiology, Heart Institute University of São Paulo Medical School São Paulo Brazil.
Peter J SchwartzCenter for Cardiac Arrhythmias of Genetic Origin, Istituto Auxologico Italiano, IRCCS Milan Italy.
Jon SkinnerSydney Childrens Hospital Network University of Sydney Sydney Australia.
Christoph StellbrinkDepartment of Cardiology and Intensive Care Medicine University Hospital Campus Klinikum Bielefeld Bielefeld Germany.
Jacob Tfelt-HansenThe Department of Cardiology, the Heart Centre, Copenhagen University Hospital, Rigshopitalet, Copenhagen, Denmark; Section of genetics, Department of Forensic Medicine, Faculty of Medical Sciences University of Copenhagen Denmark.
Thomas DenekeHeart Center Bad Neustadt Bad Neustadt a.d. Saale Germany.

Funding

Medical Research Council MC_UP_1102/20
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID35936045
PMCPMC9347209

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.