Evidence map›Paper›PMID 35936005›Full record

ArticleFrontiers in immunology2022

METTL3 inhibits inflammation of retinal pigment epithelium cells by regulating NR2F1 in an m

Jiayu Meng, Xianyang Liu, Shiyun Tang, Yusen Liu, Chenyang Zhao, Qian Zhou, Na Li, Shengping Hou

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Regulation of mCell biology and toxicology · 2026
    Review
  4. Muscone Attenuates Uveitis Through the PI3K/AKT Signaling Pathway.Investigative ophthalmology & visual science · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. DNA 5mC and RNA mInternational journal of molecular sciences · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiayu MengThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xianyang LiuThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Shiyun TangThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yusen LiuThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chenyang ZhaoThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Qian ZhouThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Na LiCollege of Basic Medicine, Chongqing Medical University, Chongqing, China.
Shengping HouThe First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNNational Clinical Research Center for Digestive Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N

Indexed as

LipopolysaccharidesRetinal Pigment EpitheliumCOUP Transcription Factor IHumansInflammationInterleukin-6MethyltransferasesOccludinRNACOUP Transcription Factor IInterleukin-6LipopolysaccharidesMethyltransferasesMETTL3 protein, humanNR2F1 protein, humanOccludinRNAinflammationM6AMETTL3NR2F1RPE

Identifiers

PMID35936005
PMCPMC9351451
OpenAlexW4286494943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.