Evidence map›Paper›PMID 35936004›Full record

ArticleFrontiers in immunology2022

Characterization of KRAS Mutational Regression in Oligometastatic Patients.

Alessandro Ottaiano, Roberta Penta de Vera d'Aragona, Anna Maria Trotta, Mariachiara Santorsola, Maria Napolitano, Giosuè Scognamiglio, Fabiana Tatangelo, Paolo Grieco, Silvia Zappavigna, Vincenza Granata and 11 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

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  14. Immunotherapy Assessment: A New Paradigm for Radiologists.Diagnostics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Alessandro OttaianoIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Roberta Penta de Vera d'AragonaOncohaematology Department, Azienda Ospedaliera di Rilievo Nazionale (A.O.R.N.) Santobono-Pausilipon di Napoli, Naples, Italy.
Anna Maria TrottaIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Mariachiara SantorsolaIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Maria NapolitanoIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Giosuè ScognamiglioIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Fabiana TatangeloIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Paolo GriecoDepartment of Pharmacy, University of Naples "Federico II", Naples, Italy.
Silvia ZappavignaDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Vincenza GranataIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Francesco PerriIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Amalia LuceDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Giovanni SavareseAMES, Centro Polidiagnostico Strumentale srl, Naples, Italy.
Monica IannielloAMES, Centro Polidiagnostico Strumentale srl, Naples, Italy.
Marika CasilloAMES, Centro Polidiagnostico Strumentale srl, Naples, Italy.
Nadia PetrilloAMES, Centro Polidiagnostico Strumentale srl, Naples, Italy.
Andrea BelliIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Francesco IzzoIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Guglielmo NastiIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Michele CaragliaDepartment of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Stefania ScalaIstituto Nazionale Tumori di Napoli, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) "G. Pascale", Naples, Italy.
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversity of Campania "Luigi Vanvitelli" · ITBiogem · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We previously reported rare regressive genetic trajectories of Methods: Survival and prognostic impact of disease extent in 140 metastatic CRC patients were evaluated through the Kaplan-Meyer curves and the Log-Rank test. Results: The oligometastatic status was a strong and independent variable for survival (HR: 0.08 vs. polymetastatic disease; 95% CI: 0.02-0.26; Conclusions: We provide evidence that CD3

Indexed as

Colonic NeoplasmsColorectal NeoplasmsProto-Oncogene Proteins p21(ras)HumansMutationPrognosisKRAS protein, humanProto-Oncogene Proteins p21(ras)colorectal cancercytotoxicityHLAKRASoligo-metastatic disease

Identifiers

PMID35936004
PMCPMC9354788
OpenAlexW4286716986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.