Evidence map›Paper›PMID 35936002›Full record

ArticleFrontiers in immunology2022

Nano-silica particles synergistically IgE-mediated mast cell activation exacerbating allergic inflammation in mice.

Yong-Shi Yang, Meng-Da Cao, An Wang, Qing-Mei Liu, Dan-Xuan Zhu, Ying Zou, Ling-Ling Ma, Min Luo, Yang Shao, Dian-Dou Xu and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. The Potential Role ofMicroorganisms · 2025
    Review
  3. Review
  4. Review
  5. Silica nanoparticles in medicine: overcoming pathologies through advanced drug delivery, diagnostics, and therapeutic strategies.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Yong-Shi YangDepartment of Allergy, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Meng-Da CaoResearch Division of Clinical Pharmacology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
An WangBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Qing-Mei LiuDepartment of Allergy, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Dan-Xuan ZhuWomen and Children Central Laboratory, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ying ZouShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China.
Ling-Ling MaBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Min LuoBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Yang ShaoBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Dian-Dou XuBeijing Engineering Research Center of Radiographic Techniques and Equipment, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Ji-Fu WeiResearch Division of Clinical Pharmacology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jin-Lyu SunDepartment of Allergy, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.
Institute of High Energy Physics · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNChinese Academy of Sciences · CNJiangsu Province Hospital · CNNanjing Medical University · CNPeking Union Medical College Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Allergic respiratory diseases have increased dramatically due to air pollution over the past few decades. However, studies are limited on the effects of inorganic components and particulate matter with different particle sizes in smog on allergic diseases, and the possible molecular mechanism of inducing allergies has not been thoroughly studied. Methods: Four common mineral elements with different particle sizes in smog particles were selected, including Al Results: Only 20 nm SiO Conclusion: Our results indicated that nano-SiO

Indexed as

AsthmaHypersensitivityLung InjuryAnimalsbeta-N-AcetylhexosaminidasesDisease Models, AnimalHumansImmunoglobulin EInflammationMast CellsMiceMitogen-Activated Protein KinasesSilicon DioxideSmogbeta-N-AcetylhexosaminidasesImmunoglobulin EMitogen-Activated Protein KinasesSilicon DioxideSmogallergic asthmaMAPKmast cellsilica nanoparticlessmog particles

Identifiers

PMID35936002
PMCPMC9355306
OpenAlexW4286559944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.