Evidence map›Paper›PMID 35935925›Full record

ArticleFederal practitioner : for the health care professionals of the VA, DoD, and PHS2022

Gadolinium Deposition Disease: A Case Report and the Prevalence of Enhanced MRI Procedures Within the Veterans Health Administration.

D Bradley Jackson, Terence MacIntyre, Vianey Duarte-Miramontes, Joshua DeAguero, G Patricia Escobar, Brent Wagner

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Federal practitioner : for the health care professionals of the VA, DoD, and PHS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Gadolinium-Based Contrast Agents and the Theater of Safety.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  2. Response to Dr. Do.Magnetic resonance imaging · 2026
    Article
  3. Observational
  4. Review
  5. Article
  6. Gadolinium Intermediate Elimination and Persistent Symptoms After Magnetic Resonance Imaging Contrast Agent Exposure.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

D Bradley JacksonNew Mexico Veterans Administration Health Care System, Albuquerque.
Terence MacIntyreNew Mexico Veterans Administration Health Care System, Albuquerque.
Vianey Duarte-MiramontesNew Mexico Veterans Administration Health Care System, Albuquerque.
Joshua DeAgueroNew Mexico Veterans Administration Health Care System, Albuquerque.
G Patricia EscobarNew Mexico Veterans Administration Health Care System, Albuquerque.
Brent WagnerNew Mexico Veterans Administration Health Care System, Albuquerque.
University of New Mexico · US

Funding

UNM HSC Clinical and Translational Science CenterUL1TR001449 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J, PANDHI, NANCY · 2015 to 2024
$36.9M
Unfolded Protein Response and Autophagy in T Helper Cell Effector FunctionP20GM121176 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI June Bryan de la Pena · 2017 to 2026
$24.9M
Chemokine Receptors in MRI Contrast-Induced Organ FibrosisR01DK102085 · NIDDK · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI WAGNER, BRENT · 2014 to 2017
$1.2M
Fibrocyte Contribution to Systemic Fibrosis in Chronic Kidney DiseaseI01BX001958 · VA · SOUTH TEXAS VETERANS HEALTH CARE SYSTEM · PI WAGNER, BRENT · 2014 to 2017
–
BLRD VA I01 BX001958NCATS NIH HHS UL1 TR001449NIDDK NIH HHS R01 DK102085NIGMS NIH HHS P20 GM121176
6 · The paper itself

Abstract

Background: Gadolinium (Gd) usage in the Veterans Health Administration is increasing and patients with renal disease are frequently exposed. Gd is not entirely eliminated within 24 hours after administration, which may pose long-term adverse effects. Case Presentation: A Vietnam-era veteran aged > 70 years presented for evaluation of Gd-based contrast agent-induced chronic multisymptom illness. In the course of his routine clinical care, he was exposed to repeated Gd-enhanced magnetic resonance imaging studies. After his second Gd-based contrast agent exposure, he noted rash, pain, headaches, and hoarseness. Years after the exposure to the contrast agents, he continued to have detectable Gd in urine and serum. Conclusions: Practitioners should be aware of long-term intracellular Gd retention (including the brain) as patients increasingly turn to consultants with concerns about Gd deposition disease. Data from patient advocates demonstrate that Gd is eliminated in intermediate and long phases, which may represent a multicompartment model. The commercialization of Gd use in imaging studies is outpacing the science addressing the long-term consequences of harboring this alien, toxic, nonphysiologic rare earth metal.

Identifiers

PMID35935925
PMCPMC9351733
OpenAlexW4288057641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.