Evidence map›Paper›PMID 35935799›Full record

ArticleFrontiers in medicine2022

Outcomes in AB0 Incompatible Living Donor Kidney Transplantation: A Case - Control Study.

Martina Cozzi, Paola Donato, Gabriele Ugolini, Rostand Emmanuel Nguefouet Momo, Francesco Nacchia, Zeno Ballarini, Pierluigi Piccoli, Maurizio Cantini, Chiara Caletti, Stefano Andreola and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Impact of Repeated Non-Fatal Infections on Quality of Life and Graft Function in ABO-Incompatible Kidney Transplants.Transplant infectious disease : an official journal of the Transplantation Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Martina CozziKidney Transplant Center, Department of Surgical Sciences, University and Hospital Trust of Verona, Verona, Italy.
Paola DonatoKidney Transplant Center, Department of Surgical Sciences, University and Hospital Trust of Verona, Verona, Italy.
Gabriele UgoliniKidney Transplant Center, Department of Surgical Sciences, University and Hospital Trust of Verona, Verona, Italy.
Rostand Emmanuel Nguefouet MomoKidney Transplant Center, Department of Surgical Sciences, University and Hospital Trust of Verona, Verona, Italy.
Francesco NacchiaKidney Transplant Center, Department of Surgical Sciences, University and Hospital Trust of Verona, Verona, Italy.
Zeno BallariniKidney Transplant Center, Department of Surgical Sciences, University and Hospital Trust of Verona, Verona, Italy.
Pierluigi PiccoliTransfusion Medicine Unit, Department of Pathology and Diagnostic Services, University and Hospital Trust of Verona, Verona, Italy.
Maurizio CantiniTransfusion Medicine Unit, Department of Pathology and Diagnostic Services, University and Hospital Trust of Verona, Verona, Italy.
Chiara CalettiRenal Unit, Department of Medicine, University and Hospital Trust of Verona, Verona, Italy.
Stefano AndreolaNephrology Postgraduate School, Department of Medicine, University of Verona, Verona, Italy.
Giorgio GandiniTransfusion Medicine Unit, Department of Pathology and Diagnostic Services, University and Hospital Trust of Verona, Verona, Italy.
Giovanni GambaroNephrology Postgraduate School, Department of Medicine, University of Verona, Verona, Italy.
Luigino BoschieroKidney Transplant Center, Department of Surgical Sciences, University and Hospital Trust of Verona, Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients waiting for a kidney transplant by far exceed available organs. AB0 incompatible living donor kidney transplantation (AB0i LDKT) represents an additional therapeutic strategy, but with higher risk for complications. We aimed at evaluating outcomes of AB0i LDKTs compared to compatible (AB0c) controls at our Institution. Methods: Retrospective matched case - control study (1:2) comparing AB0i vs. AB0c LDKTs from March 2012 to September 2021. Considered outcomes: graft function, acute rejection, sepsis, CMV infection, BK virus reactivation, death-censored graft survival, patient survival. Results: Seventeen AB0i LDKTs matched to 34 AB0c controls. We found excellent graft function, comparable in the two groups, at all considered intervals, with an eGFR (ml/min/1.73 m Conclusions: AB0i LDKT is an effective therapeutic strategy with graft function and survival comparable to AB0c LDKTs, despite higher rates of acute rejection and sepsis. It is an additional opportunity for patients with less chances of being transplanted, as blood group 0 individuals.

Indexed as

AB0 incompatibledesensitizationisoagglutinin titerkidney transplantliving donor kidney transplantation

Identifiers

PMID35935799
PMCPMC9353324
OpenAlexW4286716368

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.