ReviewFrontiers in cardiovascular medicine2022
Four-dimensional flow cardiac magnetic resonance assessment of left ventricular diastolic function.
Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Multi-Organ Phenotypes of Offspring Born Following Hypertensive Disorders of Pregnancy: A Systematic Review.Journal of the American Heart Association · 2024Pooled it
- Cardiac morphology and flow dynamics in children born to hypertensive pregnancies.European heart journal. Imaging methods and practice · 2026Article
- 3D Phase Contrast Using Balanced Steady-State Free Precession (PC-SSFP) for Improved 4D Flow at Clinical Field Strengths.Magnetic resonance in medicine · 2026Article
- Automated 4D flow MRI pipeline for the quantification of advanced hemodynamic parameters in the left atrium.Scientific reports · 2026Article
- Multidimensional cardiac functional phenotyping beyond ejection fraction: a multimodality imaging framework for cardiovascular care.Frontiers in cardiovascular medicine · 2026Review
- Evaluating biventricular diastolic function using cardiovascular magnetic resonance 4d-flow derived E/e'.European heart journal. Imaging methods and practice · 2026Article
- Characterizing growth and early hemodynamic inefficiencies: Phase-contrast magnetic resonance imaging analysis of the aorta in post-Fontan hypoplastic left heart syndrome.JTCVS structural and endovascular · 2025Article
- 4D flow MRI-based grading of left ventricular diastolic dysfunction: a validation study against echocardiography.European radiology · 2025Article
- Cardiac magnetic resonance imaging in the assessment of cardiac injury and toxicity from cancer-related chemotherapy.Pediatric radiology · 2025Review
- Left ventricular flow dynamics by cardiac imaging techniques in heart failure patients: state of the art.Cardiovascular ultrasound · 2025Review
- The Role of Advanced Cardiac Imaging in Monitoring Cardiovascular Complications in Patients with Extracardiac Tumors: A Descriptive Review.Journal of cardiovascular development and disease · 2024Review
- Feasibility of 4D-flow CMR for haemodynamic characterization in hypertrophic cardiomyopathy after septal myectomy with and without anterior mitral valve leaflet extension.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Intracardiac fluid dynamic analysis: available techniques and novel clinical applications.BMC cardiovascular disorders · 2024Review
- Cardiac MRI in heart failure with preserved ejection fraction.La Radiologia medica · 2024Review
- The value of blood flow velocity and pressure gradient in differentiating patients with different types of heart failure.Quantitative imaging in medicine and surgery · 2024Article
- Heart failure with preserved ejection fraction: diagnosis, risk assessment, and treatment.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Review
- How to use MRI in cardiac disease with diastolic dysfunction?The British journal of radiology · 2024Review
- Cardiac Magnetic Resonance Imaging in Heart Failure.Cardiovascular innovations and applications · 2024Article
- Direct comparison of whole heart quantifications between different retrospective and prospective gated 4D flow CMR acquisitions.Frontiers in cardiovascular medicine · 2024Article
- Advanced Imaging Technologies for Assessing Tetralogy of Fallot: Insights Into Flow Dynamics.CJC pediatric and congenital heart disease · 2023Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Left ventricular diastolic dysfunction is a major cause of heart failure and carries a poor prognosis. Assessment of left ventricular diastolic function however remains challenging for both echocardiography and conventional phase contrast cardiac magnetic resonance. Amongst other limitations, both are restricted to measuring velocity in a single direction or plane, thereby compromising their ability to capture complex diastolic hemodynamics in health and disease. Time-resolved three-dimensional phase contrast cardiac magnetic resonance imaging with three-directional velocity encoding known as '4D flow CMR' is an emerging technology which allows retrospective measurement of velocity and by extension flow at any point in the acquired 3D data volume. With 4D flow CMR, complex aspects of blood flow and ventricular function can be studied throughout the cardiac cycle. 4D flow CMR can facilitate the visualization of functional blood flow components and flow vortices as well as the quantification of novel hemodynamic and functional parameters such as kinetic energy, relative pressure, energy loss and vorticity. In this review, we examine key concepts and novel markers of diastolic function obtained by flow pattern analysis using 4D flow CMR. We consolidate the existing evidence base to highlight the strengths and limitations of 4D flow CMR techniques in the surveillance and diagnosis of left ventricular diastolic dysfunction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.