Evidence map›Paper›PMID 35935589›Full record

ArticleJournal of immunology research2022

Age-Stratified Analysis of Vaginal Microbiota Dysbiosis and the Relationship with HPV Viral Load in HPV-Positive Women.

Mingzhu Li, Chao Zhao, Yun Zhao, Jingran Li, Lihui Wei

Abstract read
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. The dual roles ofFrontiers in oncology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mingzhu LiDepartment of Obstetrics and Gynecology, Peking University People's Hospital, No. 11 Xizhimen South St, Beijing 100044, China.ORCID https://orcid.org/0000-0002-0937-7862
Chao ZhaoDepartment of Obstetrics and Gynecology, Peking University People's Hospital, No. 11 Xizhimen South St, Beijing 100044, China.
Yun ZhaoDepartment of Obstetrics and Gynecology, Peking University People's Hospital, No. 11 Xizhimen South St, Beijing 100044, China.
Jingran LiDepartment of Obstetrics and Gynecology, Peking University People's Hospital, No. 11 Xizhimen South St, Beijing 100044, China.
Lihui WeiDepartment of Obstetrics and Gynecology, Peking University People's Hospital, No. 11 Xizhimen South St, Beijing 100044, China.ORCID https://orcid.org/0000-0002-2478-8790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study evaluated the distribution of vaginal microbiota dysbiosis and the association with HPV viral load test in high-risk HPV-positive women before and after 50 years old. Methods: For this cross-sectional study, 388 HPV-positive women prior to referral to colposcopy in Peking University Peoples' Hospital were included and classified as younger than 50 years ( Results: The community state type (CST) IV was the most common CST occurring in 148 women (38.1%). The proportion of CST IV in those aged 50 years or older was significantly higher than those younger than 50 years (women) (66.7% vs. 30.6%); the difference was statistically significant (<0.001). CST distribution has no statistical difference in different grades of cervical lesion, regardless of the age ( Conclusions: In women younger than 50 years, higher HPV16/18 load was more closely associated with CST IV; however, it had no significant correlation in women aged 50 years or older.

Indexed as

MicrobiotaPapillomavirus InfectionsCross-Sectional StudiesDysbiosisFemaleHuman papillomavirus 16Human papillomavirus 18HumansMiddle AgedViral Load

Identifiers

PMID35935589
PMCPMC9348945

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.