Evidence map›Paper›PMID 35935494›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Enhanced efficiency of generating human-induced pluripotent stem cells using Lin28-30Kc19 fusion protein.

Boram Son, Hyungro Yoon, Jina Ryu, Haein Lee, Jinmyoung Joo, Hee Ho Park, Tai Hyun Park

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Boram SonDepartment of Bioengineering, Hanyang University, Seoul, South Korea.
Hyungro YoonInterdisciplinary Program in Bioengineering, Seoul National University, Seoul, South Korea.
Jina RyuInterdisciplinary Program in Bioengineering, Seoul National University, Seoul, South Korea.
Haein LeeSchool of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul, South Korea.
Jinmyoung JooDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, South Korea.
Hee Ho ParkDepartment of Bioengineering, Hanyang University, Seoul, South Korea.
Tai Hyun ParkInterdisciplinary Program in Bioengineering, Seoul National University, Seoul, South Korea.
Seoul National University · KRHanyang University · KRUlsan National Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induced pluripotent stem cells (iPSCs) have intrinsic properties, such as self-renewal ability and pluripotency, which are also shown in embryonic stem cells (ESCs). The challenge of improving the iPSC generation efficiency has been an important issue and there have been many attempts to develop iPSC generation methods. In this research, we added Lin28, known as one of the reprogramming factors, in the form of a soluble recombinant protein from

Indexed as

30Kc19fusion proteinhuman induced pluripotent stem cells (hiPSCs)Lin28soluble

Identifiers

PMID35935494
PMCPMC9354855
OpenAlexW4286561792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.