Evidence map›Paper›PMID 35935488›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Human Pluripotent Stem Cell-Derived Micropatterned Ectoderm Allows Cell Sorting of Meso-Endoderm Lineages.

Yang Yang, Cecilia Laterza, Hannah T Stuart, Federica Michielin, Onelia Gagliano, Anna Urciuolo, Nicola Elvassore

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Bioengineering gradients for controlled embryo and organ modeling.Current opinion in biomedical engineering · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Yang YangDepartment of Industrial Engineering (DII), University of Padova, Padova, Italy.
Cecilia LaterzaDepartment of Industrial Engineering (DII), University of Padova, Padova, Italy.
Hannah T StuartDepartment of Industrial Engineering (DII), University of Padova, Padova, Italy.
Federica MichielinFondazione Ricerca Biomedica Avanzata Onlus, Veneto Institute of Molecular Medicine, Padova, Italy.
Onelia GaglianoDepartment of Industrial Engineering (DII), University of Padova, Padova, Italy.
Anna UrciuoloFondazione Ricerca Biomedica Avanzata Onlus, Veneto Institute of Molecular Medicine, Padova, Italy.
Nicola ElvassoreDepartment of Industrial Engineering (DII), University of Padova, Padova, Italy.
University of Padua · ITGreat Ormond Street Hospital · GBCittà della Speranza Foundation · ITVeneto Institute of Molecular Medicine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human developmental processes during the early post-implantation stage instruct the specification and organization of the lineage progenitors into a body plan. These processes, which include patterning, cell sorting, and establishment of the three germ layers, have been classically studied in non-human model organisms and only recently, through micropatterning technology, in a human-specific context. Micropatterning technology has unveiled mechanisms during patterning and germ layer specification; however, cell sorting and their segregation in specific germ layer combinations have not been investigated yet in a human-specific

Indexed as

cell sortingectodermhPSC differentiationhuman in vitro modelmicropatterning

Identifiers

PMID35935488
PMCPMC9354750
OpenAlexW4286488092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.