Evidence map›Paper›PMID 35935327›Full record

ArticleContrast media & molecular imaging2022

CCL3 Promotes Proliferation of Colorectal Cancer Related with TRAF6/NF-

Xiaoqiang Ma, Jinda Su, Shaohui Zhao, Yaqin He, Shuzhen Li, Xiaoliang Yang, Sifan Zhai, Shikuo Rong, Xin Zhang, Guangxian Xu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 16 citations in OpenAlex.

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  10. Exosomal CircMFN2 Enhances the Progression of Pituitary Adenoma via the MiR-146a-3p/TRAF6/NF-κB Pathway.Journal of neurological surgery. Part A, Central European neurosurgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Xiaoqiang Ma *Department of Colorectal Surgery, General Hospital of Ningxia Medical University, Yinchuan 750003, China.
Jinda Su *College of Clinical Medicine, Ningxia Medical University, Yinchuan 750004, China.
Shaohui Zhao *College of Clinical Medicine, Ningxia Medical University, Yinchuan 750004, China.
Yaqin HeSurgical Department, General Hospital of Ningxia Medical University, Yinchuan 750003, China.
Shuzhen LiOperating Room, General Hospital of Ningxia Medical University, Yinchuan 750003, China.
Xiaoliang YangSurgical Department, Lingwu Traditional Chinese Medicine Hospital, Yinchuan 750499, China.
Sifan ZhaiDepartment of Colorectal and Anal Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Shikuo RongDepartment of General Surgery, Chengdu Second People's Hospital, Chengdu 610021, China.
Xin ZhangCollege of Clinical Medicine, Ningxia Medical University, Yinchuan 750004, China.
Guangxian XuInstitute of Clinical Laboratory Medicine, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical University, School of Medical Technology, Dongguan 523000, China.ORCID 0000-0002-0481-9625
Xiaoliang XieDepartment of Colorectal Surgery, General Hospital of Ningxia Medical University, Yinchuan 750003, China.ORCID 0000-0002-0832-7249
Ningxia Medical University · CNChengdu Second People's Hospital · CNFirst Affiliated Hospital of Zhengzhou University · CNGuangdong Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokine C-C motif chemokine ligand 3 (CCL3) plays an important role in the invasion and metastasis of malignant tumors. For developing new therapeutic targets and antitumor drugs, the effect of chemokine CCL3 and the related cytokine network on colorectal cancer should be investigated. This study used cell, tissue, and animal experiments to prove that CCL3 is highly expressed in colorectal cancer and confirmed that CCL3 can promote the proliferation of cancer cells, and its expression is closely related to TRAF6/NF-

Indexed as

Colorectal NeoplasmsNF-kappa BAnimalsCell Line, TumorCell MovementCell ProliferationChemokine CCL3TNF Receptor-Associated Factor 6Chemokine CCL3NF-kappa BTNF Receptor-Associated Factor 6

Identifiers

PMID35935327
PMCPMC9296340
OpenAlexW4285093724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.