Evidence map›Paper›PMID 35935217›Full record

ArticleFrontiers in microbiology2022

Impact of a phage cocktail targeting

Colin Buttimer, Tom Sutton, Joan Colom, Ellen Murray, Pedro H Bettio, Linda Smith, Andrei S Bolocan, Andrey Shkoporov, Akihiko Oka, Bo Liu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Bacteriophage-mediated reduction of uropathogenicbioRxiv : the preprint server for biology · 2025
    Article
  11. Review
  12. Review
  13. Isolation and characterization ofMicrobiology spectrum · 2024
    Article
  14. Article
  15. Review
  16. Review
  17. Characterization of anFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Colin ButtimerAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Tom SuttonAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Joan ColomAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Ellen MurrayAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Pedro H BettioAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Linda SmithAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Andrei S BolocanAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Andrey ShkoporovAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Akihiko OkaCenter for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Bo LiuCenter for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Jeremy W HerzogCenter for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
R Balfour SartorCenter for Gastrointestinal Biology and Disease, Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Lorraine A DraperAPC Microbiome Ireland, University College Cork, Cork, Ireland.
R Paul RossAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Colin HillAPC Microbiome Ireland, University College Cork, Cork, Ireland.
University College Cork · IEAPC Microbiome Institute · IEUniversity of North Carolina at Chapel Hill · US

Funding

PILOT AND FEASIBILITY STUDIESP30DK034987 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Temitope O. Keku · 1985 to 2026
$30.5M
Role of IL-10 in APC Regulation of Protective vs. Pathogenic T Cell Responses toP01DK094779 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SARTOR, RYAN B · 2013 to 2023
$17.9M
National Gnotobiotic Rodent Resource CenterP40OD010995 · OD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Ryan B Sartor · 2012 to 2026
$9.7M
NIDDK NIH HHS P01 DK094779NIDDK NIH HHS P30 DK034987NIH HHS P40 OD010995
6 · The paper itself

Abstract

Escherichia coli and

Indexed as

bacteria consortiumbacteriophageEnterococcus faecalisEscherichia colifermentationgutmurine modelphage cocktail therapy

Identifiers

PMID35935217
PMCPMC9355613
OpenAlexW4286685374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.