Evidence map›Paper›PMID 35935176›Full record

ArticleeNeurologicalSci2022

Neurological manifestations by sex and age group in COVID-19 inhospital patients.

Daniella Nunes Pereira, Maria Aparecida Camargos Bicalho, Alzira de Oliveira Jorge, Angélica Gomides Dos Reis Gomes, Alexandre Vargas Schwarzbold, Anna Luiza Homan Araújo, Christiane Corrêa Rodrigues Cimini, Daniela Ponce, Danyelle Romana Alves Rios, Genna Maira Santos Grizende and 12 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in eNeurologicalSci, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Characteristics of Oral Adverse Effects following COVID-19 Vaccination and Similarities with Oral Symptoms in COVID-19 Patients: Taste and Saliva Secretory Disorders.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Review
  2. A suitable model to investigate acute neurological consequences of coronavirus infection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 15 institutions in 3 countries.

Daniella Nunes PereiraFaculdade de Medicina, Universidade Federal de Minas Gerais, Brazil.
Maria Aparecida Camargos BicalhoFaculdade de Medicina, Universidade Federal de Minas Gerais, Brazil.
Alzira de Oliveira JorgeFaculdade de Medicina, Universidade Federal de Minas Gerais, Brazil.
Angélica Gomides Dos Reis GomesHospitais da Rede Mater Dei, Brazil.
Alexandre Vargas SchwarzboldHospital Universitário de Santa Maria/EBSERH; Universidade Federal de Santa Maria, Brazil.
Anna Luiza Homan AraújoHospital Universitário Ciências Médicas, Brazil.
Christiane Corrêa Rodrigues CiminiHospital Santa Rosália, Brazil.
Daniela PonceHospital das Clínicas da Faculdade de Medicina de Botucatu, Brazil.
Danyelle Romana Alves RiosComplexo da Saúde São João de Deus, Universidade Federal de São João del-Rei, Brazil.
Genna Maira Santos GrizendeSanta Casa de Misericórdia de Belo Horizonte, Brazil.
Euler Roberto Fernandes ManentiHospital Mãe de Deus, Brazil.
Fernando AnschauGrupo Hospitalar Conceição, Brazilian National Health System, Hospital Nossa Senhora da Conceição and Hospital Cristo Redentor, Brazil.
Fernando Graça AranhaHospital SOS Cárdio, Brasil.
Frederico BartolazziHospital Santo Antônio, Brasil.
Joanna d'Arc Lyra BatistaUniversidade Federal Fronteira do Sul, Brasil.
Julia Teixeira TupinambásHospital Metropolitano Odilon Behrens, Brazil.
Karen Brasil RuschelHospital Mãe de Deus, Hospital Universitário de Canoas, Universidade Federal do Rio Grande do Sul e Instituto de Avaliação de Tecnologia em Saúde (IATS/CNPQ), Brazil.
Maria Angélica Pires FerreiraHospital de Clínicas de Porto Alegre; IATS/CnPq, Brazil.
Pedro Gibson ParaísoOrizonti- Instituto Oncomed de Saúde e Longevidade, Brazil.
Silvia Ferreira AraújoHospital Semper, Brazil.
Antonio Lucio TeixeiraFaculdade Santa Casa BH, Brazil.
Milena Soriano MarcolinoDepartment of Internal Medicine, Medical School, and Telehealth Center, University Hospital, Universidade Federal de Minas Gerais, Brazil.
Hospital Mãe de Deus · BRNational Council for Scientific and Technological Development · BRFaculdade de Ciências Médicas de Minas Gerais · BRFederal University of São João del-Rei · BRFundação Hospitalar do Estado de Minas Gerais · BRGrupo Santa Casa de Belo Horizonte · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRHospital de Santo António · PTHospital Nossa Senhora da Conceição · BRHospital Risoleta Tolentino Neves · BRHospital Universitário de Santa Maria · BRMater Dei Hospital · BRUniversidade Federal da Fronteira Sul · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal dos Vales do Jequitinhonha e Mucuri · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Neurological manifestations have been associated with a poorer prognosis in COVID-19. However, data regarding their incidence according to sex and age groups is still lacking. Methods: This retrospective multicentric cohort collected data from 39 Brazilian hospitals from 17 cities, from adult COVID-19 admitted from March 2020 to January 2022. Neurological manifestations presented at hospital admission were assessed according to incidence by sex and age group. Results: From 13,603 COVID-19 patients, median age was 60 years old and 53.0% were men. Women were more likely to present with headaches (22.4% vs. 17.7%, Conclusion: Older COVID-19 patients were more likely to present delirium, syncope and coma, while the incidence of anosmia, ageusia and headaches decreased with age. Women were more likely to present headache, and less likely to present seizures.

Indexed as

ACE2, Angiotensin-converting enzyme 2AD, Alzheimers diseaseAgeBMI, Body mass indexCI, Confidence intervalCNS, Central nervous systemCOPD, Chronic obstructive pulmonary diseaseCOVID-19DeliriumIQR, Interquartile rangeNeurological manifestationsOR, Odds ratioSex

Identifiers

PMID35935176
PMCPMC9338167
OpenAlexW4288808564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.