Evidence map›Paper›PMID 35935138›Full record

ArticleResearch (Washington, D.C.)2022

Comprehensive Humoral and Cellular Immune Responses to SARS-CoV-2 Variants in Diverse Chinese Population.

Jiwei Li, Jing Wu, Qiuyue Long, Yan'an Wu, Xiaoyi Hu, Yukun He, Mingzheng Jiang, Jia Li, Lili Zhao, Shuoqi Yang and 13 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Research (Washington, D.C.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. The CD38Frontiers in immunology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 2 institutions in 1 country.

Jiwei LiDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Jing WuDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Qiuyue LongDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Yan'an WuDepartment of Clinical Laboratory, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Xiaoyi HuDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Yukun HeDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.
Mingzheng JiangDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Jia LiDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.
Lili ZhaoDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing, China.
Shuoqi YangSchool of Medicine, Xiamen University, Xiamen, Fujian, China.
Xiaoyong ChenDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Minghui WangDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Jianshi ZhengDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Fangfang WuDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Ruiliang WuDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Lihong RenDepartment of Pediatrics, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Liang BuDepartment of Thoracic Surgery, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Houzhao WangDepartment of Clinical Laboratory, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Ke LiDepartment of Critical Care Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Lijuan FuDepartment of Infectious Diseases, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.
Guojun ZhangCancer Research Center and The Department of Breast-Thyroid-Surgery, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.ORCID https://orcid.org/0000-0001-5182-5887
Yali ZhengDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.ORCID https://orcid.org/0000-0002-0359-2799
Zhancheng GaoDepartment of Respiratory, Critical Care and Sleep Medicine, Xiang'an Hospital of Xiamen University, Xiamen, Fujian, China.ORCID https://orcid.org/0000-0002-8495-9221
Xiamen University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 variants have been emerging and have made great challenges to current vaccine and pandemic control strategies. It is urgent to understand the current immune status of various Chinese populations given that the preexisting immunity has been established by national vaccination or exposure to past variants. Using sera from 85 individuals (including 21 convalescents of natural infection, 15 cases which suffered a breakthrough infection after being fully vaccinated, and 49 healthy vaccinees), we showed significantly enhanced neutralizing activities against SRAS-CoV-2 variants in convalescent sera, especially those who had been fully vaccinated. The neutralizing antibodies against Omicron were detectable in 75% of convalescents and 44.9% of healthy vaccinees (

Identifiers

PMID35935138
PMCPMC9275105
OpenAlexW4283329818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.