Evidence map›Paper›PMID 35935001›Full record

ArticleJournal of machine learning research : JMLR2021

Inference for the Case Probability in High-dimensional Logistic Regression.

Zijian Guo, Prabrisha Rakshit, Daniel S Herman, Jinbo Chen

Abstract read
In one paragraph

Article in Journal of machine learning research : JMLR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Inference for Deep Neural Network Estimators in Generalized Nonparametric Models.Journal of the American Statistical Association · 2026
    Article
  3. Statistics in medicine · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zijian GuoDepartment of Statistics, Rutgers University, Piscataway, New Jersey, USA.
Prabrisha RakshitDepartment of Statistics, Rutgers University, Piscataway, New Jersey, USA.
Daniel S HermanDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jinbo ChenDepartment of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

Semi-supervised Approaches to Denoising Electronic Health Records Data for Risk PredictionR01LM013614 · NLM · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CAI, TIANXI, GUO, ZIJIAN · 2021 to 2024
$1.4M
Statistical Methods for Analyzing Electronic Health Record DataR01HL138306 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHEN, JINBO · 2018 to 2020
$1.2M
Predictive Modeling with High-Dimensional lncomplete DataR01GM140463 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI GUO, ZIJIAN · 2020 to 2022
$560k
Statistical Methods for Analyzing Electronic Health Record DataR56HL138306 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHEN, JINBO · 2017 to 2017
$396k
NHLBI NIH HHS R01 HL138306NHLBI NIH HHS R56 HL138306NIGMS NIH HHS R01 GM140463NLM NIH HHS R01 LM013614
6 · The paper itself

Abstract

Labeling patients in electronic health records with respect to their statuses of having a disease or condition, i.e. case or control statuses, has increasingly relied on prediction models using high-dimensional variables derived from structured and unstructured electronic health record data. A major hurdle currently is a lack of valid statistical inference methods for the case probability. In this paper, considering high-dimensional sparse logistic regression models for prediction, we propose a novel bias-corrected estimator for the case probability through the development of linearization and variance enhancement techniques. We establish asymptotic normality of the proposed estimator for any loading vector in high dimensions. We construct a confidence interval for the case probability and propose a hypothesis testing procedure for patient case-control labelling. We demonstrate the proposed method via extensive simulation studies and application to real-world electronic health record data.

Indexed as

Case-controlContraction principleEHR phenotypingOutcome labellingRe-weighting

Identifiers

PMID35935001
PMCPMC9354733

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.