Evidence map›Paper›PMID 35934731›Full record

ArticlePediatrics2022

Adolescent Use of Flavored Non-Tobacco Oral Nicotine Products.

Alyssa F Harlow, Erin A Vogel, Alayna P Tackett, Junhan Cho, Dae-Hee Han, Melissa Wong, Myles G Cockburn, Steve Y Sussman, Jennifer B Unger, Adam M Leventhal and 1 more

Open access · greenAbstract read
In one paragraph

Article in Pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 66 citations in OpenAlex.

  1. Trial
  2. Evaluating the Role of Nicotine Stereoisomer on Nicotine Pouch Abuse Liability: A Randomized Crossover Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Trial
  3. Trial
  4. Willingness to Use Commercial Nicotine Gums, Lozenges, and Gummies Among Nontobacco Using Adolescents in Southern California.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Nontobacco Nicotine Dependence as a Risk Factor for Poor Long-Term Outcomes After Shoulder Arthroplasty and Rotator Cuff Repair.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  12. Article
  13. Article
  14. Multilevel Correlates of Same Day Poly-Product Use/Co-Use among Adolescents Who Use Tobacco and Cannabis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  15. Article
  16. Article
  17. Methods for Vaping Cessation Among Young Adults in Southern California.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Alyssa F HarlowUSC Institute for Addiction Science.
Erin A VogelUSC Institute for Addiction Science.
Alayna P TackettUSC Institute for Addiction Science.
Junhan ChoUSC Institute for Addiction Science.
Dae-Hee HanUSC Institute for Addiction Science.
Melissa WongUSC Institute for Addiction Science.
Myles G CockburnUSC Institute for Addiction Science.
Steve Y SussmanUSC Institute for Addiction Science.
Jennifer B UngerUSC Institute for Addiction Science.
Adam M LeventhalUSC Institute for Addiction Science.
Jessica L Barrington-TrimisUSC Institute for Addiction Science.
USC Norris Comprehensive Cancer Center · US

Funding

USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jessica Louise Barrington-Trimis · 2018 to 2026
$39.0M
Vaping Nicotine and Cannabis Across Adolescence and Young AdulthoodR01CA229617 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE, LEVENTHAL, ADAM MATTHEW · 2019 to 2024
$4.3M
Tobacco Use Treatment Research for Vulnerable PopulationsK24DA048160 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam Matthew Leventhal · 2019 to 2026
$1.4M
Understanding Transitions from Vaping to Smoking Across AdolescenceK01DA042950 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE · 2017 to 2021
$1.0M
Respiratory effects of E-Cigarette use among Youth: A prospective, longitudinal investigationK01HL148907 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TACKETT, ALAYNA PAULINE · 2019 to 2023
$981k
NCI NIH HHS R01 CA229617NCI NIH HHS U54 CA180905NHLBI NIH HHS K01 HL148907NIDA NIH HHS K01 DA042950NIDA NIH HHS K24 DA048160
6 · The paper itself

Abstract

BACKGROUND AND

objectivesFlavored non-tobacco oral nicotine products (eg, nicotine pouches and nontherapeutic nicotine gum, lozenges, tablets, gummies), are increasingly marketed in the United States. Prevalence of non-tobacco oral nicotine product use among adolescents is unknown.

methodsWe calculated prevalence of ever and past 6-month use of nicotine pouches, other non-tobacco oral nicotine products (ie, gum, lozenges, tablets, and/or gummies), e-cigarettes, cigarettes, hookah or waterpipe, cigars, cigarillos, and snus among high school students in Southern California between September and December 2021. Generalized linear mixed models tested associations of sociodemographic factors and tobacco-product use with use of any non-tobacco oral nicotine product.

resultsAmong the sample (n = 3516), prevalence was highest for e-cigarettes (ever: 9.6%, past 6-month: 5.5%), followed by non-tobacco oral nicotine products (ever: 3.4%, past 6-month: 1.7%), and <1% for other products. Ever users of combustible tobacco (adjusted odds ratio [aOR] = 77.6; 95% confidence interval [CI] = 39.7-152) and ever users of noncombustible tobacco (aOR = 40.4; 95% CI= 24.3-67.0) had higher odds of ever using non-tobacco oral nicotine products, compared to never users of combustible and noncombustible tobacco. Use of any non-tobacco oral nicotine product was greater for Hispanic (versus all other races/ethnicities except Asian, aOR = 2.58; 95% CI = 1.36-4.87), sexual minority (versus heterosexual, aOR=1.63; 95% CI = 1.03-2.57), gender minority (versus male, aOR = 2.83; 95% CI = 1.29-6.19), and female (versus male, aOR=1.92, 95% CI = 1.20-3.06) participants.

conclusionsNon-tobacco oral nicotine products were the second most prevalent nicotine product used by adolescents. They were disproportionately used by certain racial or ethnic, sexual, or gender minority groups, and those with a history of nicotine use. Adolescent non-tobacco oral nicotine product use surveillance should be a public health priority.

Indexed as

Electronic Nicotine Delivery SystemsTobacco ProductsTobacco Use DisorderAdolescentFemaleFlavoring AgentsHumansMaleNicotineTobacco UseUnited StatesFlavoring AgentsNicotine

Identifiers

PMID35934731
PMCPMC9994602
OpenAlexW4290596794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.