ArticleMicrobial cell factories2022
Mnsod1 promotes the development of Pleurotus ostreatus and enhances the tolerance of mycelia to heat stress.
Article in Microbial cell factories, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Molecular biology of Pleurotus mushrooms: genomic resources, genetic manipulation, and regulation mechanisms.Antonie van Leeuwenhoek · 2026Review
- Screening of Heat-ResistantBiology · 2026Article
- The Interference ofJournal of fungi (Basel, Switzerland) · 2026Article
- Analysis of Volatile Organic Compounds and Comparison of Heat Resistance Related Gene Expression inMycobiology · 2026Article
- Family Identification and Functional Study of Copper Transporter Genes inInternational journal of molecular sciences · 2024Article
- Current Advances in the Functional Genes of Edible and Medicinal Fungi: Research Techniques, Functional Analysis, and Prospects.Journal of fungi (Basel, Switzerland) · 2024Review
- Function of Transcription FactorsInternational journal of molecular sciences · 2023Article
- Nitric Oxide Negatively Regulates the Rapid Formation ofJournal of fungi (Basel, Switzerland) · 2022Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundSuperoxide dismutases (SODs, EC 1.15.1.1) are defense proteins that can be used as sweepers to clear reactive oxygen species (ROS). They have been widely studied in the plant. Intensive research demonstrates that SOD plays an essential role in plants. However, in Pleurotus ostreatus, the function and regulatory pathway of SOD in the growth and development and the abiotic stress response have not been clear.
resultsIn this study, three MnSOD-encoding genes of the P. ostreatus CCMSSC00389 strain were cloned and identified. Mnsod1, Mnsod2, and Mnsod3 were interrupted by 3, 7, and 2 introns, and encoded proteins of 204, 220, and 344 amino acids, respectively. By comparing the relative expression of three MnSOD-encoding genes in mycelia, the results showed that the gene with the highest primary expression was Mnsod1. Subsequently, the function of P. ostreatus Mnsod1 was explored by overexpression (OE) and RNA interference (RNAi). The results showed that during the growth and development of P. ostreatus, MnSOD1 protein increased gradually from mycelia to the fruiting body, but decreased in spores. The change of Mnsod1 transcription level was not consistent with the changing trend of MnSOD1 protein. Further studies showed that during primordia formation, the expression of Mnsod1 gradually increased, reaching a peak at 48 h, and the transcription level was 2.05-folds compared to control. H
conclusionsThis study indicates that Mnsod1 plays an active role in the formation of P. ostreatus primordia and the response to abiotic stress.
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