Evidence map›Paper›PMID 35933704›Full record

ArticleCell proliferation2022

Manufacturing with pluripotent stem cells (PSConf 2021): Key issues for future research and development.

Glyn N Stacey, Jingyi Cao, Baoyang Hu, Qi Zhou

Abstract read
In one paragraph

Article in Cell proliferation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. MSC Manufacture.Advances in experimental medicine and biology · 2025
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Glyn N StaceyInternational Stem Cell Banking Initiative, Barley, Herts, UK.ORCID https://orcid.org/0000-0003-2987-0328
Jingyi CaoInstitute for Stem Cell and Regenerative Medicine, Chinese Academy of Sciences, Beijing, China.
Baoyang HuInstitute for Stem Cell and Regenerative Medicine, Chinese Academy of Sciences, Beijing, China.ORCID https://orcid.org/0000-0003-3993-4014
Qi ZhouInstitute for Stem Cell and Regenerative Medicine, Chinese Academy of Sciences, Beijing, China.ORCID https://orcid.org/0000-0002-6549-9362

Funding

Chinese Academy of Sciences President's International Fellowship for Special Experts 2018FSB0009National Key Research and Development Program of China 2017YFE0122900National Natural Science Foundation of China 31621004Strategic Priority Research Program of the Chinese Academy of Sciences XDA16030000
6 · The paper itself

Abstract

Human pluripotent stem cells (hPSC) have the capability to deliver novel cell-based medicines that could transform medical treatments for a wide range of diseases including age-related degenerative disorders and traumatic injury. In spite of significant investment in this area, due to the novel nature of these hPSC-based medicines, there are challenges in almost all aspects of their manufacturing including bioprocessing, characterization and delivery. The Chinese Academy of Sciences and the Chinese Society for Stem Cell Research have collaborated to create a new discussion forum called PSConf 2021 (Pluripotent Stem Cell Conference 2021), intended to promote exchanges in communication on cutting-edge developments and international coordination in hPSC manufacturing. The PSConf 2021 addressed crucial topics in stem cell-based manufacturing, including stem cell differentiation, culture scale-up, product formulation and release. This report summarizes the proceedings and conclusions from the discussion sessions, and it is accompanied by publication of individual papers from the speakers at the PSConf 2021. SIGNIFICANCE STATEMENT: The PSConf 2021 meeting has brought together speakers and delegates from more than 20 countries in an informal discussion forum focusing on the manufacture of cell-based medicines using hPSCs. The conference discussion sessions enabled an open exchange of information on the latest developments, ideas on key challenges and their potential solutions. It also captured the experiences and lessons learnt by professionals who had been in the field from the earliest applications of human embryonic stem cells, and presented a diverse range of new potential pluripotent stem cell-based medicines that are now under development, with some already in clinical trials.

Indexed as

Cell Culture TechniquesPluripotent Stem CellsCell DifferentiationHumansResearch

Identifiers

PMID35933704
PMCPMC9357356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.