Evidence map›Paper›PMID 35933612›Full record

ArticleMedical physics2023

A novel QA phantom based on scintillating fiber ribbons with implementation of 2D dose tomography for small-field radiotherapy.

Josué Esteves, Odran Pivot, Julien Ribouton, Patrice Jalade, Abdelaali Zouaoui, Laurent Desbat, Simon Rit, Frédéric Blanc, Guido Haefeli, Plamen Hopchev and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Josué EstevesUniv Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, Ecole Centrale de Lyon, CPE Lyon, INL, UMR5270, Villeurbanne, France.
Odran PivotUniv. Grenoble Alpes, CNRS, Grenoble INP, TIMC, Grenoble, France.
Julien RiboutonService de Radiophysique et Radiovigilance, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Patrice JaladeService de Radiophysique et Radiovigilance, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Abdelaali ZouaouiUniv Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, Ecole Centrale de Lyon, CPE Lyon, INL, UMR5270, Villeurbanne, France.
Laurent DesbatUniv. Grenoble Alpes, CNRS, Grenoble INP, TIMC, Grenoble, France.
Simon RitUniv Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1294, CREATIS, Lyon, France.
Frédéric BlancLPHE EPFL, Lausanne, Switzerland.
Guido HaefeliLPHE EPFL, Lausanne, Switzerland.
Plamen HopchevLPHE EPFL, Lausanne, Switzerland.
Jean-Marc GalvanUniv Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, Ecole Centrale de Lyon, CPE Lyon, INL, UMR5270, Villeurbanne, France.
Guo-Neng LuUniv Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, Ecole Centrale de Lyon, CPE Lyon, INL, UMR5270, Villeurbanne, France.
Patrick PittetUniv Lyon, Université Claude Bernard Lyon 1, CNRS, INSA Lyon, Ecole Centrale de Lyon, CPE Lyon, INL, UMR5270, Villeurbanne, France.
École Polytechnique Fédérale de Lausanne · CHÉcole Centrale de Lyon · FRHôpital Lyon Sud · FRInstitut des Nanotechnologies de Lyon · FRCentre de Recherche en Acquisition et Traitement de l'Image pour la Santé · FRCentre National de la Recherche Scientifique · FRÉcole d'Ingénieurs en Chimie et Sciences du Numérique · FRUniversité Grenoble Alpes · FR

Funding

Investissements d'Avenir ANR-11-IDEX-0007ITMO Cancer AVIESAN 18CP125-00LABEX PRIMES ANR-11-LABX-0063Swiss National Science Foundation 166208
6 · The paper itself

Abstract

purposeTo develop a novel instrument for real-time quality assurance (QA) procedures in radiotherapy. The system implements a scintillation-based phantom and associated signal acquisition and processing modules and aims to monitor two-dimensional (2D) dose distributions of small fields. MATERIALS AND

methodsFor the proposed phantom, we have designed and realized a prototype implementing six high-resolution tissue-equivalent scintillating fiber ribbons stacked with in-plane 30° rotated orientations from each other. Each ribbon output is coupled to a silicon photodiode linear array (with an element pitch of 400 μm) to detect scintillating signal, which represents the projected irradiation profile perpendicular to the ribbon's orientation. For the system providing six acquired projected dose profiles at different orientations, we have developed a two-step signal processing method to perform 2D dose reconstruction. The first step is to determine irradiation field geometry parameters using a tomographic geometry approach, and the second one is to perform specific penumbra estimation. The QA system prototype has been tested on a Novalis TrueBeam STX with a 6-MV photon beam for small elliptic fields defined by 5- and 10-mm cone collimators and for 10 × 10- and 20 × 10-mm

resultsThe reconstructed 2D dose distributions have gamma index pass rates higher than 95% for all the tested configurations as compared with EBT3 film measurements with both 2%-DD/700-μm-DTA and 1%-DD/1-mm criteria. 2D global gamma analysis shows that the two-step and FBP radiation field reconstruction methods systematically outperform the SIRT approach. Moreover, higher gamma index success rates are obtained with the two-step method than with FBP in the case of the fields defined with the stereotactic cones.

conclusionsThe proposed small-field QA system makes a use of six water-equivalent scintillating detectors (fiber ribbons) to acquire dose distribution. The developed two-step signal processing method performs tomographic 2D dose reconstruction. A system prototype has been built and tested using hospital facilities with small rectangular and elliptic fields. Testing results show 2D reconstructed dose distributions with high accuracy and resolution. Such a system could potentially be an alternative approach to film dosimetry for small-field QA, which is still widely used as reference in clinical practice.

Indexed as

RadiometryTomographyImaging, Three-DimensionalPhantoms, ImagingRadiotherapy DosageRadiotherapy Planning, Computer-AssistedWaterWater2D dose tomographysmall-field dosimetrywater-equivalent scintillating detectors

Identifiers

PMID35933612
PMCPMC10087208
OpenAlexW4292120385

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.