Evidence map›Paper›PMID 35933595›Full record

ArticleAdvanced healthcare materials2022

Living Biomaterials to Engineer Hematopoietic Stem Cell Niches.

Michaela Petaroudi, Aleixandre Rodrigo-Navarro, Oana Dobre, Matthew J Dalby, Manuel Salmeron-Sanchez

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Probiotic-Based Materials as Living Therapeutics.Advanced materials (Deerfield Beach, Fla.) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michaela PetaroudiCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8LT, UK.
Aleixandre Rodrigo-NavarroCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8LT, UK.
Oana DobreCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8LT, UK.
Matthew J DalbyCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8LT, UK.
Manuel Salmeron-SanchezCentre for the Cellular Microenvironment, University of Glasgow, Glasgow, G12 8LT, UK.ORCID 0000-0002-8112-2100
University of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Living biointerfaces are a new class of biomaterials combining living cells and polymeric matrices that can act as biologically active and instructive materials that host and provide signals to surrounding cells. Here, living biomaterials based on Lactococcus lactis to control hematopoietic stem cells in 2D surfaces and 3D hydrogels are introduced. L. lactis is modified to express C-X-C motif chemokine ligand 12 (CXCL12), thrombopoietin (TPO), vascular cell adhesion protein 1 (VCAM1), and the 7th-10th type III domains of human plasma fibronectin (FN III

Indexed as

FibronectinsThrombopoietinBiocompatible MaterialsHematopoietic Stem CellsHumansHydrogelsLigandsBiocompatible MaterialsFibronectinsHydrogelsLigandsThrombopoietincell engineeringgenetic engineeringhematopoiesisliving materialsmicroenvironment engineeringstem cellssynthetic biology

Identifiers

PMID35933595
PMCPMC11469072
OpenAlexW4290273673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.